Heart Rate Turbulence and Clinical Prognosis in Hypertrophic Cardiomyopathy and Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Short-term fluctuations in sinus cycle length after a single ventricular premature complex (VPC) have attracted considerable interest and has been termed heart rate turbulence (HRT). The onset and slope of HRT have each been reported to be independent and powerful predictors of clinical prognosis in patients with myocardial infarction (MI), but there are no data available for patients with hypertrophic cardiomyopathy (HCM). Thus the present study analyzed the 2 HRT variables to determine their prognostic value in HCM patients. Holter monitoring data were obtained from 104 HCM patients, 44 MI patients and 56 normal controls, from which singular VPCs followed by ≥20 normal sinus beats were isolated and the HRT onset and slope were automatically calculated. HRT onset and slope were abnormal in MI patients, but not in HCM patients, as compared with normal control subjects (onset -1.1±2.9, -2.1±3.4, -1.4±5.1% ; slope 10.6±8.6, 18.0±13.9, 16.6±9.7ms/beat, respectively). During the follow-up period of 27±10 months, 7 HCM patients and 10 MI patients either died from cardiac death or were hospitalized for congestive heart failure. In MI patients, HRT onset was higher and the HRT slope was lower in patients with cardiac events than in patients without (onset 1.1±2.7 vs -1.7±2.7%, p=0.011 ; slope 5.7±4.3 vs 12.0±9.0ms/beat, p=0.028). In HCM patients, however, the HRT onset and slope were similar between patients with and without cardiac events (onset -2.0±2.0 vs -2.1±3.5%, p=0.98 ; slope 18.1±10.9 vs 18.0±14.0ms/beat, p=0.68). In conclusion, unlike MI patients, the HRT variables in selected HCM patients were not abnormal and failed to predict the clinical prognosis. (Circ J 2003 : 67 : 601-604)
- 社団法人日本循環器学会の論文
- 2003-06-20
著者
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Hadase Mitsuyoshi
Department of Cardiology, Saiseikai Shigaken Hospital
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AZUMA Akihiro
Department of Cardiology, National Shiga Hospital
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Sugihara H
Department Of Cardiology Matsushita Memorial Hosipital
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Azuma Akihiro
Second Department of Medicine, Kyoto Prefectural University of Medicine
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Hadase Mitsuyoshi
Kyoto First Red Cross Hospital
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Hadase Mitsuyoshi
Departments Of Cardiology Kyoto First Red Cross Hospital
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Hadase Mitsuyoshi
Department Of Cardiology Saiseikai Shigaken Hospital
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Hadase Mitsuyoshi
Department Of Cardiology Kyoto First Red Cross Hospital
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Asada Satoshi
Department Of Cardiovascular Medicine Kyoto Prefectural Universtiy Of Medicine
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Asada Satoshi
Department Of Cardiology Akashi Municipal Hospital
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Kawasaki Tatsuya
Department of Cardiology, Matsushita Memorial Hospital, Japan
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Kamitani Tadaaki
Department of Cardiology, Matsushita Memorial Hospital, Japan
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Kuribayashi Toshiro
Kuribayashi Clinic of Cardiology
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Sugihara Hiroki
Department of Cardiology, Matsushita Memorial Hospital
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Kamitani Tadaaki
Department Of Cardiology Matsushita Memorial Hosipital
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Kamide Takashi
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Kawasaki Shingo
Department of Cardiology, Matsushita Memorial Hospital
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Azuma Akihiro
The Second Department Of Medicine Kyoto Prefectural University Of Medicine
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SHIRAISHI Hirokazu
the Kyoto Prefectural Yosanoumi Hospital
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Kawasaki Tatsuya
Department Of Cardiology Matsushita Memorial Hosipital
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Kamide Takashi
Department Of Cardiology Matsushita Memorial Hospital
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Hadase Mitsuyoshi
Departments Of Cardiovascular Medicine Kyoto Prefectural University School Of Medicine
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Kawasaki Shingo
Department Of Cardiology Matsushita Memorial Hospital
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Sugihara Hiroki
Department Of Cardiology Kyoto Prefectural University Of Medicine
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Shiraishi Hirokazu
京都府立与謝の海病院
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Kuribayashi Toshiro
Second Department Of Medicine Kyoto Prefectural University Of Medicine.
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Katahira Toshio
Kuribayashi Clinic Of Cardiology
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Kuribayashi Toshiro
The Second Dept. Of Anat. Kyoto Pref. Univ. Of Med
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Kuribayashi Toshiro
Department Of Anatomy Kyoto Prefectural University Of Medicine
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Kusaba Tetsuro
Division Of Cardiology And Nephrology Department Of Medicine Kyoto Prefectural University Of Medicin
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Asada Satoshi
Department Of Cardiology Matsushita Memorial Hospital
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Sugihara Hiroki
The 2nd. Dept. Of Int. Med. Kyoto Pref. Univ. Of Med.
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Azuma Akihiro
Second Department Of Medicine Kyoto Prefectural University Of Medicine
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AZUMA Akihiro
Second Department of Medicine and, Kyoto Prefectural University of Medicine
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