Arisugacins C and D, Novel Acetyicholinesterase Inhibitors and Their Related Novel Metabolites Produced by Penicillium sp. FO-4259-11
スポンサーリンク
概要
- 論文の詳細を見る
- 2000-01-25
著者
-
Omura Satoshi
Research Center For Biological Function The Kitasato Institute And School Of Pharmaceutical Sciences
-
SUNAZUKA Toshiaki
Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Science
-
MASUMA Rokuro
Research Center for Biological Function, The Kitasato Institute
-
IWAI Yuzuru
Research Center for Biological Function, The Kitasato Institute
-
SHIOMI Kazuro
Research Center for Biological Function, The Kitasato Institute, and School of Pharmaceutical Scienc
-
OTOGURO KAZUHIKO
Research Center for Tropical Diseases, The Kitasato Institute
-
ARAI Noriko
Research Center for Biological Function, The Kitasato Institute
-
Masuma R
Kitasato Institute For Life Sciences And Graduate School Of Infection Control Sciences Kitasato Univ
-
Sunazuka T
信州大学医学部附属病院 薬剤部
-
Sunazuka Toshiaki
Kitasato Univ. Tokyo Jpn
-
Yamaguchi Y
The Kitasato Institute
-
YAMAGUCHI Yuuichi
Research Center for Biological Function, The Kitasato Institute
-
Arai Noriko
The Kitasato Institute
-
Suzuki Kunihiko
Research Center For Biological Function The Kitasato Institute And Pharmaceutical Sciences Kitasato
-
Otoguro Kazuhiko
Research Centre For Tropical Diseases The Kitasato Institute
-
Otoguro Kazuhiko
Kitasato Inst. Tokyo Jpn
-
Otoguro Kazuhiko
Research Center For Biological Function The Kitasato Institute
-
岩井 雄二
Faculty Of Pharmaceutical Sciences Kobe Gakuin University
-
MATSUI Ryosuke
School of Pharmaceutical Sciences Kitasato University
-
Otoguro K
Research Centre For Tropical Diseases The Kitasato Institute
-
Iwai Y
Kitasato Institute For Life Sciences Kitasato University
-
Iwai Yuzuru
Research Center For Biological Function The Kitasato Institute
-
Takamatsu S
Univ. Mississippi Ms Usa
-
Masuma R
Kitasato Institute For Life Sciences And Graduate School Of Infection Control Sciences Kitasato Univ
-
Shiomi Kazuro
Research Center For Biological Function The Kitasato Institute And School Of Pharmaceutical Sciences
-
Omura Satoshi
Research Center For Biological Function The Kitasato Institute
関連論文
- Production of the New Antibiotic Tetrahydrokalafungin by Transformants of the Kalafungin Producer Streptomyces tanashiensis
- Isolation of Restriction-reduced Mutants from Streptomyces(Microbiology & Fermentation Industry)
- Application of PCR for Selection of Gram-Positive Bacteria with High DNA G+C Content among New Isolates
- New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-Acylation/Cyclization
- Microbial Conversion of EM574 and EM523, Gastrointestinal motor Stimulating Agents
- Bioactive Metabolites of EM574 and EM523, Erythromycin Derivatives Having Strong Gastrointestinal Motor Stimulating Activity
- Vagus-Dependent and Vagus-Independent Mechanisms of Action of the Erythromycin Derivative EM574 and Motilin in Dogs
- Total Synthesis of Madindolines, Potent Selective Inhibitors of Interleukine 6, Novel Bioactive Microbial Metabolites
- Construction of a single Component Producer from the Wild Type Avermectin Producer Streptomyces avermitilis
- The Neuritogenesis Inducer Lactacystin Arrests Cell Cycle at Both Go/G1 and G2 Phases in Neuro 2a Cells
- Direct Production of 5-Oxo Derivatives of Avermectins by a Recombinant Strain of Streptomyces avermitilis
- Arohynapene D, a New Anticoccidial Agent Produced by Penicillium sp.FO-2295
- Fudecalone, a New Anticoccidial Agent Produced by Penicillium sp.FO-2030
- Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis II.Structure Elucidation of Terpendoles A, B, C and D
- Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis I.Production, Isolation and Biological Properties
- Isolation and Characterization of Covalently Closed Circular DNA Associated with Chromosomal and Membrane Fraction from Streptomyces ambofaciens
- Genetic and Biochemical Features of Spiramycin Biosynthesis in Streptomyces ambofaciens--Curing,Protoplast Regeneration and Plasmid Transfer
- Extraction and Characterization of Plasmids from Macrolide Antibiotic-Producing Streptomycetes
- Structural Modification of the Lincomycin Antibiotic
- Chemical Synthesis and Structural Study of Lincomycin Sulfoxides and a Sulfone
- Semisynthetic Modification of Antibiotic Lincomycin
- In Vitro and in Vivo Antimalarial Activities of a Non-glycosidic 18-Membered Macrolide Antibiotic, Borrelidin, against Drug-resistant Strains of Plasmodia
- Dechlorogeodin and Its New Dihydro Derivatives, Fungal Metabolites with Herbicidal Activity
- Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684 I. Producing Strain, Fermentation, Isolation, and Biological Activities
- Andrastins A-S, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. F)-3929 I. producing Strain, Fermentation, Isolation, and Biological Activities
- Herquline B, a New Platelet Aggregation Inhibitor Produced by Penicillium herquei Fg-372
- Isochromophilones III~VI, Inhibitors of Acyl-CoA:Cholesterol Acyltransferase Produced by Penicillium multicolor FO-3216
- Phenopyrrozin, a New Radical Scavenger Produced by Penicillium sp.FO-2047
- New Glycosidases Inhibitors, Panosialins D and wD Produced by StreptOmyces sp.OH-5186
- Isolation of a New Antibiotic Oligomycin G Produced by Streptomyces sp. WK-6150
- Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp. WK-5344 I. Production, Isolation and Biological Properties
- Antimalarial Activity of Radicicol, Heptelidic Acid and Other Fungal Metabolites
- Two New Components of the Aspochalasins Produced by Aspergillus sp.
- Amphistin, a New Melanogenesis Inhibitor, Produced by an Actinomycete
- Efficient Chemical Conversion of Louisianin A to C and D, The Inhibitor of Angiogenesis
- Argadin, a New Chitinase Inhibitor, Produced by Clonostachys sp.FO-7314
- Argifin, a New Chitinase Inhibitor, Produced by Gliocladium sp. FTD-0668 : I. Taxonomy, Fermentation, and Biological Activities
- Synthesis and Inhibitory Activities of Isochromophilone Analogues against gp120-CD4 Binding
- Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones
- Pyripyropenes, Novel ACAT Inhibitors Produced by Aspergillus fumigatus III.Structure Elucidation of Pyripyropenes E to L
- Synthesis and Anti-platelet Aggregation Activity of Water-soluble Staurosporine Derivatives
- Staurosporine, a Potentially Important Gift from a Microorganism
- Effect of 14-Membered Ring Macrolide Compounds on Rat Leucocyte Chemotaxis and the Structure-activity Relationships
- Effcects of Erythromycin and Its Derivatives on Interlcukin-8 Release by Human Bronchial Epithelial Cell Line BEAS-2B Cells
- Synthesis and Antiangiogenic Activity of Staurosporine Derivatives
- Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670 I. Production, Isolation and Biological Properties
- Chloropeptins, New Anti-HIV Antibiotics Inhibiting gp120-CD4 Binding from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Physico-chemical Properties and Biological Activities
- Chemical Modification and Structure-activity Relationships of Pyripyropenes 1. Modification at the Four Hydroxyl Groups
- Structure-activity Relationships of Pyripyropenes Fungal Acyl-CoA:Cholesterol Acyltransferase Inhibitors
- Heme-dependent Radical Generation from Antimalarial Fungal Metabolites, Radicicol ad Heptelidic acid
- Andrastins A-C, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. FO-3929 II. Structure Elucidation and Biosynthesis
- Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis III.Production, Isolation and Structure Elucidation of New Components
- Potent Antimalarial Activities of Polyether Antibiotic, X-206
- Funalenone, a Novel Collagenase Inhibitor Produced by Aspergillus niger
- Novel Cyclopentanone Derivatives Pentenocins A and B, with Interleukin-1βConverting Enzyme Inhibitory Activity, Produced by Trichoderma hamatum FO-6903
- Malolactomycins C and D, New 40-Membered Macrolides Active against Botrytis
- Amidepsine E, an Inhibitor of Diacylglycerol Acyltransferase Produced by Humicola sp. FO-5969
- Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase, Produced by Aspergillus niger FT-0554
- Determination of Absolute Stereochemistries of Arisugacin F and Territrem B, Novel Acetylcholinesterase Inhibitors
- Convergent Synthesis of Arisugacin Skeletons and Their Acetylcholinesterase Inhibitory Activity
- Structure-activity Relationships Study of Pyripyropenes : Reversal of Cancer Cell Multidrug Resistance
- Structure-activity Relationships of Lactacystin, the First Non-protein Neurotrophic Factor
- Pyripyropenes, Novel ACTA Inhibitors Produced by Aspergillus Fumigatus IV. Structure Elucidation of Pyripyropenes M to R
- Characterization of Actinomycetes Isolated from Fallen Leaves
- Rare Actinomycetes Isolated from Desert Soils
- Hydranthomycin, a New Agroactive Antibiotic Produced by Streptomyces sp.K93-5305
- Screening Method for Cellulose Biosynthesis Inhibitors with Herbicidal Activity
- New Brominated and Halogen-less Derivatives and Structure-activity Relationship of Azaphilones Inhibiting gp120-CD4 Binding
- Chloropeptins, New Anti-HIV Antibiotics Inhibiting gp120-CD4 Binding from Streptomyces sp. II. Structure Elucidation of Chloropeptin I
- Structure Elucidation of Roselipins, Inhibitors of Diacylglycerol Acyltransferase Produced by Gliocladium roseum KF-1040
- Roselipins, Inhibitors of Diacylglycerol Acyltransferase, Produced by Gliocladium roseum KF-1040
- Roselipins, Novel Fungal Metabolites Having a Highly Methylated Fatty Acid Modified with a Mannose and an Arabinitol
- Arisugacins C and D, Novel Acetyicholinesterase Inhibitors and Their Related Novel Metabolites Produced by Penicillium sp. FO-4259-11
- Screening and Fermentation of Endo-α-N-Acetylgalactosaminidase S, a Mucin-Hydrolyzing Enzyme from Streptomyces Acting on the GalNAc-Ο-Ser(Thr)Linkage
- New Antibiotics Phthoxazolins B, C and D Produced by Streptomyces sp.KO-7888
- Heme-dependent Radical Generation: possible Involvement in Antimalarial Action of Non-peroxide Microbial Metabolites, Nanaomycin A and Radicicol
- Isolation and Structure of a New Antibiotic Viridomycin F Produced by Streptomyces sp. K96-0188
- Transfer of Staurosporine-Producing Strain Streptomyces staurosporeus AM-2282 to the Genus Saccharothrix as Saccharothrix aerocolonigenes (Labeda 1986) subsp. staurosporeus subsp. nov.
- Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670 II. Structure Elucidation
- Screening of Antianaerobic Antibiotics and Anticoccidial Antibiotics from Microorganisms
- Argifin, a New Chitinase Inhibitor, Produced by Gliocladium sp. FTD-0668 : II. Isolation, Physico-chemical Properties, and Structure Elucidation
- Andrastin D, Novel Protein Farnesyltransferase Inhibitor Produced by Penicillium sp. FO-3929
- Kurasoins A and B, New Protein Farnesyltransferase Inhibitors Produced by Paecilomyces sp. FO-3684 II. Structure Elucidation and Total Synthesis
- Arisugacins A and B, Novel and Selective Acetylcholinesterase Inhibitors from Penicillium sp. FO-4259
- Physiological Regulation of Sporulation of Kitasatosporia setae in Submerged Culture
- Chemical Modification and Structure-activity Relationships of Pyripyropenes 2. 1,11-Cyclic Analogs
- Syntheses and Absolute Structures of Novel Protein Farnesyltransferase Inhibitors, Kurasoins A and B
- Chemical Modification and Structure-activity Relationships of Pyripyropenes 3. Synthetic Conversion of Pyridine-pyrone Moiety
- Inhibition of Cholesteryl Ester Transfer Protein by Fungal Metabolites, L681,512
- Xanthoquinodin B3, a New Anticoccidial Agent Produced by Humicola sp. FO-888
- Arisugacin, a Novel and Selective Inhibitor of Acetylcholinesterase from Penicillium sp.FO-4259
- Erabulenols, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Penicillium sp. FO-5637 I. Production, Isolation and Biological Properties
- Arisugacins A and B, Novel and Selective Acetylcholinesterase Inhibitors from Penicillium sp. FO-4259 II. Structure Elucidation
- Amidepsines, Inhibitors of Diacylglycerol Acyltransferase Produced by Humicola sp.FO-2942 I.Production, Isolation and Biological Properties
- Amidepsines, Inhibitors of Diacylglycerol Acyltransferase Produced by Humicola sp.FO-2942 II.Structure Elucidation of Amidepsines A, B and C
- Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp. WK-5344 II. Structure Elucidation
- Erabulenols, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Penicillium sp. FO-5637 II. Structure Elucidation of Erabulenols A and B
- New Isochromphilones VII and VIII Produced by Penicillium sp. FO-4164
- Lactacystin, a Proteasome Inhibitor : Discovery and its Application in Cell Biology
- In vitro and in vivo antitrypanosomal activities of three peptide antibiotics : leucinostatin A and B, alamethicin I and tsushimycin