Roselipins, Novel Fungal Metabolites Having a Highly Methylated Fatty Acid Modified with a Mannose and an Arabinitol

スポンサーリンク

概要

• 論文の詳細を見る
• 1999-06-25

著者

• Namikoshi Michio

  Tohoku Pharmaceutical University

• Abe Tatsuo

  Tokyo University Of Fisheries

• Omura Satoshi

  Research Center For Biological Function The Kitasato Institute And School Of Pharmaceutical Sciences

• TOMODA Hiroshi

  Research Center for Biological Function, The Kitasato Institute and School of Pharmaceutical Science

• TABATA Noriko

  Research Center for Biological Function, The Kitasato Institute

• Tomoda Hiroshi

  Research Center For Biological Function The Kitasatc Institute

• NAMIKOSHI Michio

  Tokyo University of Fisheries

• Namiki Mikie

  Department Of Ocean Sciences Tokyo University Of Fisheries

• Tabata Noriko

  Kitasato Institute For Life Sciences & Graduate School Of Infection Control Sciences Kitasato Un

• Tabata N

  Department Of Microbiology Hoshi College Of Pharmacy

• OHYAMA Yukako

  Research Center for Biological Function, The Kitasato Institute

• Natori Masahiko

  College Of Agriculture And Veterinary Medicine Nihon University

• Ohyama Yukako

  Kitasato Institute For Life Sciences & Graduate School Of Infection Control Sciences Kitasato Un

• Omura Satoshi

  Research Center For Biological Function The Kitasato Institute

関連論文

• Isolation of salsolinol, a Tetrahydroisoquinoline alkaloid, from the marine sponge Xestospongia cf. vansoesti as a proteasome inhibitor
• Production of the New Antibiotic Tetrahydrokalafungin by Transformants of the Kalafungin Producer Streptomyces tanashiensis
• Isolation of Restriction-reduced Mutants from Streptomyces(Microbiology & Fermentation Industry)
• Isolation of Salsolinol, a Tetrahydroisoquinoline Alkaloid, from the Marine Sponge Xestospongia cf. vansoesti as a Proteasome Inhibitor
• Application of PCR for Selection of Gram-Positive Bacteria with High DNA G+C Content among New Isolates
• New Analogs of the Pyripyropene Family of ACAT Inhibitors via α-Pyrone Fragmentation and γ-Acylation/Cyclization
• Microbial Conversion of EM574 and EM523, Gastrointestinal motor Stimulating Agents
• Bioactive Metabolites of EM574 and EM523, Erythromycin Derivatives Having Strong Gastrointestinal Motor Stimulating Activity
• Vagus-Dependent and Vagus-Independent Mechanisms of Action of the Erythromycin Derivative EM574 and Motilin in Dogs
• Total Synthesis of Madindolines, Potent Selective Inhibitors of Interleukine 6, Novel Bioactive Microbial Metabolites
• Construction of a single Component Producer from the Wild Type Avermectin Producer Streptomyces avermitilis
• The Neuritogenesis Inducer Lactacystin Arrests Cell Cycle at Both Go/G1 and G2 Phases in Neuro 2a Cells
• Direct Production of 5-Oxo Derivatives of Avermectins by a Recombinant Strain of Streptomyces avermitilis
• Arohynapene D, a New Anticoccidial Agent Produced by Penicillium sp.FO-2295
• Fudecalone, a New Anticoccidial Agent Produced by Penicillium sp.FO-2030
• Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis II.Structure Elucidation of Terpendoles A, B, C and D
• Terpendoles, Novel ACAT Inhibitors Produced by Albophoma yamanashiensis I.Production, Isolation and Biological Properties
• Isolation and Characterization of Covalently Closed Circular DNA Associated with Chromosomal and Membrane Fraction from Streptomyces ambofaciens
• Genetic and Biochemical Features of Spiramycin Biosynthesis in Streptomyces ambofaciens--Curing,Protoplast Regeneration and Plasmid Transfer
• Extraction and Characterization of Plasmids from Macrolide Antibiotic-Producing Streptomycetes
• Structural Modification of the Lincomycin Antibiotic
• Chemical Synthesis and Structural Study of Lincomycin Sulfoxides and a Sulfone
• Semisynthetic Modification of Antibiotic Lincomycin
• Dechlorogeodin and Its New Dihydro Derivatives, Fungal Metabolites with Herbicidal Activity
• Andrastins A-S, New Protein Farnesyltransferase Inhibitors Produced by Penicillium sp. F)-3929 I. producing Strain, Fermentation, Isolation, and Biological Activities
• Herquline B, a New Platelet Aggregation Inhibitor Produced by Penicillium herquei Fg-372
• Macrosphelide, a Novel Inhibitor of Cell-cell Adhesion Molecule I.Taxonomy, Fermentation, Isolation and Biological Activities
• Isochromophilones III~VI, Inhibitors of Acyl-CoA:Cholesterol Acyltransferase Produced by Penicillium multicolor FO-3216
• Phenopyrrozin, a New Radical Scavenger Produced by Penicillium sp.FO-2047
• New Glycosidases Inhibitors, Panosialins D and wD Produced by StreptOmyces sp.OH-5186
• Phenochalasins, Inhibitors of Lipid Droplet Formation in Mouse Macrophages, Produced by Phomopsis sp. FT-0211
• Isolation of a New Antibiotic Oligomycin G Produced by Streptomyces sp. WK-6150
• Ferroverdins, Inhibitors of Cholesteryl Ester Transfer Protein Produced by Streptomyces sp. WK-5344 I. Production, Isolation and Biological Properties
• Antimalarial Activity of Radicicol, Heptelidic Acid and Other Fungal Metabolites
• Two New Components of the Aspochalasins Produced by Aspergillus sp.
• Macrosphelides C and D, Novel Inhibitors of Cell Adhesion
• Amphistin, a New Melanogenesis Inhibitor, Produced by an Actinomycete
• Efficient Chemical Conversion of Louisianin A to C and D, The Inhibitor of Angiogenesis
• Macrosphelide, a Novel Inhibitor of Cell-cell Adhesion Molecule II. Physicochemical Properties and Structural Elucidation
• Argadin, a New Chitinase Inhibitor, Produced by Clonostachys sp.FO-7314
• Argifin, a New Chitinase Inhibitor, Produced by Gliocladium sp. FTD-0668 : I. Taxonomy, Fermentation, and Biological Activities
• Synthesis and Inhibitory Activities of Isochromophilone Analogues against gp120-CD4 Binding
• Promotion of IL-8 production in PMA-stimulated HL-60 cells by sesquiterpene quinones from a marine sponge, Hippospongia sp.
• P-175 STRUCTURES AND BIOLOGICAL ACTIVITIES OF SESQUITERPENE QUINONES FROM A PALAUAN MARINE SPONGE
• Structure-specific Inhibition of Cholesteryl Ester Transfer Protein by Azaphilones
• Pyripyropenes, Novel ACAT Inhibitors Produced by Aspergillus fumigatus III.Structure Elucidation of Pyripyropenes E to L
• Synthesis and Anti-platelet Aggregation Activity of Water-soluble Staurosporine Derivatives
• Staurosporine, a Potentially Important Gift from a Microorganism
• Cytotoxicity of Lissoclibadins and Lissoclinotoxins, Isolated from a Tropical Ascidian Lissoclinum cf. badium, against Human Solid-Tumor-Derived Cell Lines(Pharmacognosy)
• P-391 STRUCTURE AND BIOACTIVITY OF LISSOCLIBADINS ISOLATED FROM A TROPICAL ASCIDIAN LISSOCLINUM CF. BADIUM
• In Vitro and in Vivo Antitrypanosomal Activitiy of Two Microbial Metabolites, KS-505a and Alazopeptin
• Effect of 14-Membered Ring Macrolide Compounds on Rat Leucocyte Chemotaxis and the Structure-activity Relationships
• Effcects of Erythromycin and Its Derivatives on Interlcukin-8 Release by Human Bronchial Epithelial Cell Line BEAS-2B Cells
• Synthesis and Antiangiogenic Activity of Staurosporine Derivatives
• Zelkovamycin, a New Cyclic Peptide Antibiotic from Streptomyces sp. K96-0670 I. Production, Isolation and Biological Properties
• Chloropeptins, New Anti-HIV Antibiotics Inhibiting gp120-CD4 Binding from Streptomyces sp. I. Taxonomy, Fermentation, Isolation, and Physico-chemical Properties and Biological Activities
• P-64 New Cyclic Depsipeptides from the Hawaiian Green Alga Bryopsis Species : Utilization of Carboxypeptidase for the Absolute Stereostructure Determination
• Chemical Modification and Structure-activity Relationships of Pyripyropenes 1. Modification at the Four Hydroxyl Groups
• Structure-activity Relationships of Pyripyropenes Fungal Acyl-CoA:Cholesterol Acyltransferase Inhibitors
• 12'-Hydroxyl group remarkably reduces Roridin E cytotoxicity
• Tetrahydrobostrycin and 1-Deoxytetrahydrobostrycin, Two New Hexahydroanthrone Derivatives, from a Marine-derived Fungus Aspergillus sp.
• Three New Nardosinane Type Sesquiterpenes from an Indonesian Soft Coral Nephthea sp.
• Four New Macrocyclic Trichothecenes from Two Strains of Marine-derived Fungi of the Genus Myrothecium
• P-147 MELOPHLINS P-S, NEW TETRAMIC ACID DERIVATIVES, FROM TWO MARINE SPONGES OF THE GENUS MELOPHLUS COLLECTED IN PALAU
• Melophlins P, Q, R, and S : Four New Tetramic Acid Derivatives, from Two Palauan Marine Sponges of the Genus Melophlus
• Prevention by Polyhydroxysteroids and Saponins of Asterina pectinifera of the Desquamation of Stratum Corneum Cells(Organic Chemistry)
• Heme-dependent Radical Generation from Antimalarial Fungal Metabolites, Radicicol ad Heptelidic acid
• Selective and Potent in Vitro Antitrypanosomal Activities of Ten Microbial Metabolites
• In vitro antimalarial activity of prenylated flavonoids from Erythrina fusca
• Manoalide derivatives from a marine sponge Luffariella sp. collected in Palau
• Three New Chlorine Containing Antibiotics from a Marine-derived Fungus Aspergillus ostianus Collected in Pohnpei
• A New Screening Method for Antimitotic Substances and Isolation of Glycolipids as Stimulators of Tubulin Polymerization from Okinawan Sponge Pseudoceratina sp.
• Effect of sea water concentration on hyphal growth and antimicrobial metabolite production in marine fungi
• Cladospolide D, a New 12-Membered Macrolide Antibiotic Produced by Cladosporium sp. FT-0012
• Nafuredin, a Novel Inhibitor of NADH-fumarate Reductase, Produced by Aspergillus niger FT-0554
• Isolation and Characterization of Bioactive Metabolites form Marine-Derived Filamentous Fungi Collected from Tropical and Sub-Tropical Coral Reefs
• Structure Elucidation of Roselipins, Inhibitors of Diacylglycerol Acyltransferase Produced by Gliocladium roseum KF-1040
• Roselipins, Inhibitors of Diacylglycerol Acyltransferase, Produced by Gliocladium roseum KF-1040
• Roselipins, Novel Fungal Metabolites Having a Highly Methylated Fatty Acid Modified with a Mannose and an Arabinitol
• Simaomicin α: Effects on the Cell Cycle of Synchronized, Cultured Plasmodium falciparum
• Homoisoflavonoids and Related Compounds. V. : A Novel Dibenzoxocin Derivative from Caesalpinia sappan L.(Organic,Chemical)
• Homoisoflavonoids and Related Compounds. III. : Phenolic Constituents of Caesalpinia japonica SIEB. et ZUCC.(Organic,Chemical)
• Paecilospirone, a Unique Spiro [chroman-2, 1' (3'H)-isobenzofuran] Derivative Isolated from Tropical Marine Fungus Paecilomyces sp.^H
• Phomopsidin, a New Inhibitor of Microtubule Assembly Produced by Phomopsis sp. isolated from Coral Reef in Pohnpei
• A Screening Method for Antimitotic and Antifungal Substances Using Conidia of Pyriculaia oryzae, Modification and Application to Tropical Marine Fungi
• Spoxazomicins A-C, novle antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460^T
• Solid-phase synthesis and biological activity of malformin C and its derivatives
• Panowamycins A and B, new antitrypanosomal isochromans produced by Streptomyces sp. K07-0010
• Borrelidin, a potent antimalarial : stage-specific inhibition profile of synchronized cultures of Plasmodium falciparum
• In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A-C, produced by Penicillium sp. FKI-4410
• In vitro and in vivo antitrypanosomal activities of three peptide antibiotics : leucinostatin A and B, alamethicin I and tsushimycin
• In vitro antitrypanosomal activity of five low-MW antibiotics
• In vitro and in vivo anti-Trypanosoma brucei activities of phenazinomycin and related compounds
• Promising lead compounds for novel antiprotozoals
• Jogyamycin, a new antiprotozoal aminocyclopentitol antibiotic, produced by Streptomyces sp. a-WM-JG-16.2
• Sinefungin VA and dehydrosinefungin V, new antitrypanosomal antibiotics produced by Streptomyces sp. K05-0178
• In vitro antitrypanosomal activity of 12 low-molecular-weight antibiotics and observations of structure/activity relationships
• In vitro and in vivo antiprotozoal activities of bispolides and their derivatives
• Pyrenocine I, a new pyrenocine analog produced by Paecilomyces sp. FKI-3573
• Antitrypanosomal peptaibiotics, trichosporins B-VIIa and B-VIIb, produced by Trichoderma polysporum FKI-4452

もっと見る 閉じる

スポンサーリンク