Cytotoxic Mechanisms of FK317, a New Class of Bioreductive Agent with Potent Antitumor Activity
スポンサーリンク
概要
- 論文の詳細を見る
- 1998-06-30
著者
-
KAWAMURA Ikuo
Department of Microbiology, Kyoto University Graduate School of Medicine
-
Naoe Yoshinori
Department of Urology, Medicinal Biology Research Lab., Fujisawa Pharmaceutical Co., Ltd.
-
INAMI Masamichi
Department of Molecular Immunology and Medical Immunology, Graduate School of Medicine, Chiba Univer
-
MANDA Toshitaka
Department of Pharmacology, Pharmacological Research Laboratories, Fujisawa Pharmaceutical Co., Ltd
-
MATSUMOTO Sanae
Department of Pharmacology, Pharmacological Research Laboratories, Fujisawa Pharmaceutical Co., Ltd
-
SHIMOMURA Kyoichi
Department of Pharmacology, Pharmacological Research Laboratories, Fujisawa Pharmaceutical Co., Ltd
-
NISHIGAKI Fusako
Department of Pharmacology, Pharmacological Research Laboratories, Fujisawa Pharmaceutical Co.,Ltd.
-
TSUJIMOTO Susumu
Department of Pharmacology, Pharmacological Research Laboratories, Fujisawa Pharmaceutical Co.,Ltd.
-
Kawamura I
Fujisawa Pharmaceutical Co. Ltd. Osaka Jpn
-
Kawamura Ikuo
Department Of Bacteriology Niigata University School Of Medicine
-
Naoe Yoshinori
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Manda Toshitaka
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Matsumoto Sanae
Department Of Anesthesiology Kansai Medical University
-
Matsumoto S
Pharmacology Research Laboratories Astellas Pharma Inc.
-
Mizota Tamotsu
Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Shimomura K
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Shimomura Kyoichi
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Inami Masamichi
Department Of Immunology Graduate School Of Medicine Chiba University
-
Nishigaki Fusako
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Tsujimoto Susumu
Department Of Pharmacology Pharmacological Research Laboratories Fujisawa Pharmaceutical Co. Ltd.
-
Tsujimoto Susumu
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Okayama University Okayama
-
MANDA Toshitaka
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokyo
関連論文
- Seeligeriolysin O, a protein toxin of Listeria seeligeri, stimulates macrophage cytokine production via Toll-like receptors in a profile different from that induced by other bacterial ligands
- CP8-8 FK228, histone deacetylase inhibitor : A novel drug for the treatment of prostate and renal cancers
- Direct Comparison of the Pharmacodynamics of Four Antifungal Drugs in a Mouse Model of Disseminated Candidiasis Using Microbiological Assays of Serum Drug Concentrations
- Determination of Antifungal Activities in Serum Samples from Mice Treated with Different Antifungal Drugs Allows Detection of an Active Metabolite of Itraconazole
- CD69-null mice protected from arthritis induced with anti-type II collagen antibodies
- Prolonged skin allograft survival by IL-10 gene-introduced CD4 T cell administration
- Correlation between the Presence of Virulence-Associated Genes as Determined by PCR and Actual Virulence to Mice in Various Strains of Listeria Spp.
- New Antitumor Substances, FR901463, FR901464 and FR901465 II. Activities against Experimental Tumors in Mice and Mechanism of Action
- Reduced Activity of Anabolizing Enzymes in 5-Fluorouracil-resistant Human Stomach Cancer Cells
- Synthesis and Biological Properties of a Novel Cephalosporin FR86521 Having Potent Activity Against Methicillin-resistant Staphylococcus aureus (MRSA)
- Anti-cachectic Effect of FK317, a Novel Anti-cancer Agent, in Colon26 and LX-1 Models in Mice
- FK317, a Novel Substituted Dihydrobenzoxazine, Exhibits Potent Antitumor Activity against Human Tumor Xenografts in Nude Mice
- Different Effects of FK317 on Multidrug-resistant Tumor in vivo and in vitro
- Cytotoxic Mechanisms of FK317, a New Class of Bioreductive Agent with Potent Antitumor Activity
- A New Aromatase Inhibitor, FR901537 II.Pharmacological and Antitumor Effects
- Comparative Study of Certain Antibiotics on Epileptogenic Property, Including (1Rpi, 5S, 6S)-2-[(6,7-Dihydro-5H-pyrazolo[1,2-a] [1,2,4] triazolium-6-yl)] thio-6-[(R)-1-hydroxyethyl]-1-methyl-carbapenem-3-carboxylate (LJC10627), a Carbapenem Antibiotic wit
- Effects of a New Non : Steroidal 5α : Reductase Inhibitor, FK143, on the Prostate Gland in Beagle Dogs
- Involvement of Reactive Oxygen Intermediate in the Enhanced Expression of Virulence-Associated Genes of Listeria monocytogenes inside Activated Macrophages
- DEPTH-LIMITED OSCILLATORY BOUNDARY LAYERS ON A ROUGH BOTTOM
- Stimulation of Choleresis by Insulin-Like Growth Factor-l in Rats
- Mechanisms for 5-Fluorouracil Resistance in Human Colon Cancer DLD-1 Cells
- FR149175, a β_3-Adrenoceptor-Selective Agonist, Is a Possible Therapeutic Agent for Non-Insulin-Dependent Diabetes Mellitus
- Implication of Sensory Neurons in the Diverse Mechanisms of Adaptive Cytoprotection in the Rat Stomach
- EFFECT OF ZOTEPINE ON AFTERDISCHARGE INDUCED BY ELECTRICAL STIMULATION OF AMYGDALOID NUCLEUS IN RATS
- Mycobacterial Mammalian Cell Entry Protein 1A (Mce1A)-Mediated Adherence Enhances the Chemokine Production by A549 Alveolar Epithelial Cells
- CALCIUM IONS AND RELAXATION OF INTESTINAL SMOOTH MUSCLE INDUCED BY PAPAVERINE AND ASPAMINOL
- Effects of Cholinergic Drugs and Cerebral Metabolic Activators on Memory Impairment in Old Rats
- Use of a serum-based antifungal susceptibility assay to predict the in vivo efficacy of novel echinocandin compounds
- A patient with cardiac amyloidosis successfully managed with propofol anesthesia
- Distinct cytokine-inducing ability of Streptococcus pyogenes strains isolated from toxic shock-like syndrome cases
- THE ROLE OF CAUDATE NUCLEUS DOPAMINE AND CYCLIC AMP IN THE HYPERPYREXIA INDUCED BY LiCl PLUS TRANYLCYPROMINE IN RATS
- THE CENTRAL ANTI-SEROTONIN ACTIVITY OF ZOTEPINE, A NEW NEUROLEPTIC, IN RATS
- SIGNIFICANCE OF WITHDRAWAL JUMPING RESPONSE IN PREDICTING PHYSICAL DEPENDENCE IN MICE
- Antitumor Effects of Droloxifene, a New Antiestrogen Drug, against 7, 12-Dimethylbenz(a)anthracene-Induced Mammary Tumors in Rats.
- Effects of Quinotolast, a New Orally Active Antiallergic Drug, on Experimental Allergic Models.
- Effect of FK973, a new antitumor antibiotic, on the cell cycle of L1210 cells in vitro.
- The Estrogenic and Antiestrogenic Activities of Droloxifene in Human Breast Cancers.
- Specific metabolic activation of FK973, a new antitumor antibiotic, in L1210 leukemia cells.