Undifferentiated Carcinoma in the Cardioesophageal Junction which Produces Parathyroid Hormone Related Protein
スポンサーリンク
概要
- 論文の詳細を見る
A 68-year-old man with undifferentiated carcinoma occurring in the Cardioesophageal junction accompanied by hypercalcemia is reported. The serum level of parathyroid hormone-related protein (PTHrP) was remarkably elevated. Serum calcium and PTHrP levels decreased following chemotherapy, but this amelioration was temporary. He died of hypercalcemia. On autopsy, a significant amount of immunoreactive PTHrP was detected in the tumor tissue extract, and the tumor cells were stained strongly positive for PTHrP by immunohistochemistry. This is the first case of undifferentiated carcinoma in the gastrointestinal tract which demonstrated hypercalcemia due to PTHrP produced by the malignant tumor.(Internal Medicine 34: 695-699, 1995)
- 社団法人 日本内科学会の論文
著者
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Kohgo Yutaka
The Department Of Internal Medicine (iii) Asahikawa Medical College
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Uehara Akira
The Department Of Internal Medicine (iii) Asahikawa Medical College
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Nozu Tsukasa
The Department Of Gastoroenterology Kushiro Medical Association Hospital
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Takahashi Atsushi
The Department Of Gastoroenterology Kushiro Medical Association Hospital
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SUZUKI Tomokatsu
the Department of Pathology, Kushiro Red Cross Hospital
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Suzuki Tomokatsu
The Department Of Pathology Kushiro Red-cross Hospital
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Takahashi Atsushi
The Department Of Communications And Integrated Systems Tokyo Institute Of Technology
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