Kumai Toshio | Department of Pharmacogenomics, St. Marianna University School of Medicine

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著作論文

Irinotecan Activates p53 With Its Active Metabolite, Resulting in Human Hepatocellular Carcinoma Apoptosis
Effects of a Calcium-Channel Blocker (CV159) on Hepatic Ischemia/Reperfusion Injury in Rats: Evaluation with Selective NO/pO2 Electrodes and an Electron Paramagnetic Resonance Spin-Trapping Method
Individual Metabolic Capacity Evaluation of Cytochrome P450 2C19 by Protein and Activity in the Small Intestinal Mucosa of Japanese Pancreatoduodenectomy Patients
Expression of CYP3A4 mRNA Is Correlated With CYP3A4 Protein Level and Metabolic Activity in Human Liver
Effects of Sodium Nitroprusside on the Catecholamine Synthetic Pathway in the Adrenal Medulla of Rats
Effects of Ovariectomy and Estrogen Replacement on Aota Angiotensin-Converting Enzyme Activity in Rats
Irinotecan-Induced Apoptosis Is Inhibited by Increased P-Glycoprotein Expression and Decreased p53 in Human Hepatocellular Carcinoma Cells(Molecular and Cell Biology)
The Elucidation of the Mechanism of Weight Gain and Glucose Tolerance Abnormalities Induced by Chlorpromazine
Examination about Vascular Wall Lipid Deposition and Alteration of Fat Metabolism Aberration-related Protein out of Spontaneously Hypertensive Hyperlipidemic Rats(Atherosclerosis, Basic 5 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulati
Utilization of Human Liver Microsomes to Explain Individual Differences in Paclitaxel Metabolism by CYP2C8 and CYP3A4
Effects of Antenatal Dexamethasone on Antioxidant Enzymes and Nitric Oxide Synthase in the Rat Lung
DISTURBANCE OR RELATIVELY IMPORTANT ACTIONS OF ANTIHYPERTENSIVES, ANTIFUNGAL AGENT AND OPIATE ANTAGONIST TO THE TESTICULAR STEROIDOGENESIS IN RAT
N-Methyl-D-aspartate Induces Phosphorylation of cAMP Response Element (CRE)-Binding Protein and Increases DNA-Binding Activity of CRE in Rat Retina
Hypertension Accelerates Diabetic Nephropathy in Wistar Fatty Rats, a Model of Type 2 Diabetes Mellitus, via Mitogen-Activated Protein Kinase Cascades and Transforming Growth
Effects of Pioglitazone on Increases in Visceral Fat Accumulation and Oxidative Stress in Spontaneously Hypertensive Hyperlipidemic Rats Fed a High-Fat Diet and Sucrose Solution
Enhancement of the Coagulation System in Spontaneously Hypertensive and Hyperlipidemic Rats
Involvement of Tyrosine Hydroxylase Upregulation in Cyclosporine-Induced Hypertension
Potential of Lansoprazole as a Novel Probe for Cytochrome P450 3A Activity by Measuring Lansoprazole Sulfone in Human Liver Microsomes
Naloxone Induced Enhancement of Systolic Blood Pressure and Reduction of Hypothalamic Catecholamine Levels in Male SHR
Comparison of the Effects of Omeprazole and Rabeprazole on Ticlopidine Metabolism In Vitro
Comparative Study of Culture Conditions for Maintaining CYP3A4 and ATP-Binding Cassette Transporters Activity in Primary Cultured Human Hepatocytes
Relationship between enhancement of tyrosine hydroxylase activity and expression of hypertension in genetically androgen-sensitive spontaneously hypertensive rat (SHR)
Modulation of Systolic Blood Pressure by Estrogen Mediated Central Opioid-Catecholamine Neurone System in Female SHR
Development of Hyperfibrinogenemia in Spontaneously Hypertensive and Hyperlipidemic Rats: A Potentially Useful Animal Model as a Complication of Hypertension and Hyperlipidemia
Localization of mRNA level and Activity of Tyrosine Hydroxylase in Spontaneously Hypertensive Rats
Anesthetics, Pentobarbital Induced Reduction of Blood Pressure and Catecholamines in Brain and Plasma by the SHR and WKY
Testosterone replacement induced enhancement both in norepinephrine-release from Aorta and systolic blood pressure in orchiectomized spontaneously hypertensive rats (SHR)
Inhibition of the pathogenesis of spontaneous hypertension in SHR by gonadectomy:Difference from adrenal regeneration hypertension
Age-related Change of Pressor Response to Norepinephrine and Tyramine and its Role of Gonads in SHR
Effects of gonadectomy in response to antihypertensive agent on onekidney, DOCAsalt hypertension in rat
Gonadectomy facilitates sensitivity of pressor response to norepinephrine in spontaneously hypertensive rats
Indispensable role of gonad in hypertensinogenesis:such as SHR, 2K1C, 1K-DOCA salt and Adrenal regenerating rats
Androgen Deprivation Inhibits Anti-hypertensive Action of Captopril and Sar1, Ile8-Angiotensin II which was Closely Related to Decrease of Central Renin
Elevated Tyrosine Hydroxylase mRNA Levels in the Adrenal Medulla of Spontaneously Hypertensive Rats.
The Facilitative Effects of Testosterone on the Expression of Tyrosine Hydroxylase mRNA in Adrenal Medulla of Spontaneously Hypertensive Rats. In Vivo and In Vitro Studies
Estradiol replacement could recovered the decreased systolic blood pressure, contraly could not altered the increased NE-release from Aorta, in ovariectomized SHR
Possible Involvement of Androgen in Increased Norepinephrine Synthesis in Blood Vessels of Spontaneously Hypertensive Rats.
Mechanismus of hypertension-induction with testosterone replacement on castrated spontaneously hypertensive rat (SHR) and kinetics of blood hormone levels
Gonadectomy modulate the action of antihypertensive agents in spontaneously hypertensive rats

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