Apoptosis Induction in Cancer Cells by Ultrasound Exposure
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概要
- 論文の詳細を見る
The methods of suppressing cancer cell proliferation by ultrasound exposure were investigated to develop a new minimally invasive cancer treatment. A stainless-steel diaphragm with a bolt-clamped Langevin-type transducer (BLT) was attached to the bottom of a water tank in the ultrasound exposure system used in this study. Cancer cells of a mouse T lymphoma (EL-4) in a flask were exposed to ultrasound under various conditions of exposure time, ultrasound frequency, ultrasound waveform, and so forth. The number of cancer cells exposed to ultrasound decreased during the culturing process. In this study, it was proved by electrophoresis, enzyme activity measurement and morphological observation that cancer cell proliferation can be suppressed by apoptosis induction in cancer cells by ultrasound exposure.
- Published by the Japan Society of Applied Physics through the Institute of Pure and Applied Physicsの論文
- 2004-05-15
著者
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WATANABE Akihiro
Faculty of Engineering, Toin University of Yokohama
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SATO Toshio
Faculty of Engineering, Toin University of Yokohama
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NISHIMURA Hiroyuki
Faculty of Engineering, Toin University of Yokohama
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Takeuchi Shinichi
Faculty Of Engineering Toin University Of Yokohama
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Kawai Kazuaki
Faculty Of Engineering Toin University Of Yokohama
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Kawashima Norimichi
Faculty Of Biomedical Engineering Toin University Of Yokohama
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Watanabe Akihiro
Faculty of Engineering, Toin University of Yokohama, Kurogane-cho 1614, Yokohama, Kanagawa 225-8502, Japan
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Takeuchi Shinichi
Faculty of Biomedical Engineering, Toin University of Yokohama, 1614 Kurogane-cho, Aoba-ku, Yokohama 225-8502, Japan
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