Japanese Guideline for Adult Asthma 2014
スポンサーリンク
概要
- 論文の詳細を見る
Adult bronchial asthma (hereinafter, asthma) is characterized by chronic airway inflammation, reversible airway narrowing, and airway hyperresponsiveness. Long-standing asthma induces airway remodeling to cause intractable asthma. The number of patients with asthma has increased, and that of patients who die from asthma has decreased (1.5 per 100,000 patients in 2012). The aim of asthma treatment is to enable patients with asthma to lead a normal life without any symptoms. A good relationship between physicians and patients is indispensable for appropriate treatment. Long-term management with antiasthmatic agents and elimination of the causes and risk factors of asthma are fundamental to its treatment. Four steps in pharmacotherapy differentiate between mild and intensive treatments; each step includes an appropriate daily dose of an inhaled corticosteroid, varying from low to high. Long-acting β2-agonists, leukotriene receptor antagonists, and sustained-release theophylline are recommended as concomitant drugs, while anti-immunoglobulin E antibody therapy has been recently developed for the most severe and persistent asthma involving allergic reactions. Inhaled β2-agonists, aminophylline, corticosteroids, adrenaline, oxygen therapy, and others are used as needed in acute exacerbations by choosing treatment steps for asthma exacerbations depending on the severity of attacks. Allergic rhinitis, chronic obstructive pulmonary disease, aspirin-induced asthma, pregnancy, asthma in athletes, and cough-variant asthma are also important issues that need to be considered.
- Japanese Society of Allergologyの論文
著者
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Yamauchi Kohei
Division Of Marine Biosciences Graduate School Of Fisheries Science Hokkaido University
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Adachi Mitsuru
Department Of 1^<st> Internal Medicine Showa University
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Tohda Yuji
Department Of Pharmacy Kinki University Hospital
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Yamaguchi Masao
Division Of Hematology And Oncology Department Of Internal Medicine Hyogo College Of Medicine
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NAGASE Hiroyuki
Division of Respiratory Medicine and Allergology, Department of Medicine, Teikyo University School o
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Akiyama Kazuo
National Hospital Organization Sagamihara Hospital
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Ohta Ken
National Hospital Organization, Tokyo National Hospital
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Ichinose Masakazu
Department of Respiratory Disease, Tohoku University Graduate School of Medicine
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Sugiura Hisatoshi
Department of Respiratory Disease, Tohoku University Graduate School of Medicine
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