Hepatosplenic Gamma-delta T-cell Lymphoma Associated with Epstein-Barr Virus
スポンサーリンク
概要
- 論文の詳細を見る
Hepatosplenic gamma-delta T-cell lymphoma (HSTCL) is a rare, aggressive subset of peripheral T-cell lymphoma. It has been reported that Epstein-Barr virus (EBV) infection can cause HSTCL; however, such cases are extremely rare, with only a few cases having been reported to date. We herein report an autopsy case of HSTCL associated with EBV infection. The presence of EBV infection was confirmed in serum EBV DNA and on in-situ hybridization, and cytotoxic molecules, such as granzyme B, perforin and T-cell intracytoplasmic antigen (TIA)-1, were all positive in lymphoma cells. These findings indicate that stimulation of persistent EBV infection may have caused HSTCL in this patient.
- 一般社団法人 日本内科学会の論文
著者
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NAKANISHI Mitsuru
Department of Gastroenterology and Hematology, Hokkaido University
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HORIMOTO Hiromasa
Department of Gastroenterology and Hematology, Hokkaido University
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KOBAYASHI Tomoe
Department of Gastroenterology and Hematology, Hokkaido University
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Chuma Makoto
Department Of Gastroenterology And Hematology Hokkaido University
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Suda Goki
Department Of Gastroenterology And Hepatology Tokyo Medical And Dental University
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Sho Takuya
Department Of Gastroenterology And Hematology Hokkaido University
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Nakai Masato
Department Of Chemistry Faculty Of Science Nagoya University
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Hashino Satoshi
Department Of Gastroenterology And Hematology Hokkaido University Hospital
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Otsuka Noriyuki
Department Of Pathology Hokkaido University Graduate School Of Medicine
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TERASHITA Katsumi
Department of Gastroenterology, Hokkaido University Hospital
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Natsuizaka Mitsuteru
Department of Gastroenterology, Sapporo Hokuyu Hospital
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SAKAMOTO Naoya
Department of Bioengineering and Robotics, Graduate School of Engineering, Tohoku University
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Chuma Makoto
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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Tsunematsu Seiji
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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Fujita Hiromi
Department of Surgical Pathology, Hokkaido University Hospital, Japan
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Sato Fumiyuki
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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Tsukuda Yoko
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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Horimoto Hiromasa
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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Kobayashi Tomoe
Department of Gastroenterology and Hepatology, Hokkaido University, Graduate School of Medicine, Japan
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