多糖体キチンの鼻副鼻腔処置への応用

概要

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Chitin was used for postoperative treatment of 36 patients undergoing nasal and paranasal sinus surgery. Chitin, a mucopolysaccharide purified from the crab's crust, has an action to promote wound healing. This chitin was used in sheet or stick form or applied to the gauze.<BR>Chitin in sheet or stick form was not more useful than the conventional gelatinized sponge, which had to be changed every 24 hours due to its frangility and nonfusibility. We found that the gauze coated with chitin on both sides as thin as 2 mm was the most useful. These chitin gauzes were used in 21 patients after conchotomy and/ or deviatomy.<BR>Advantages of this tampon are as follows: 1. Its bulkiness decreased the number of tampons, three on an average, for one nasal cavity. This could save time.2. Extraction was easy and painless compared to the ordinary gauze. Disadvantages are lower pressing ability due to its elasticity and possible infections medium of chitin.
耳鼻咽喉科臨床学会の論文