Intracranial hemorrhage and oral anticoagulant drug therapy.

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概要

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• We had five cases with intracranial hemorrhage occured during long-term oral anticoagulant drug therapy (particularly warfarin therapy).<BR>Intracranial hemorrhages comprised chronic subdural hematoma in 4 cases and subcortical hematoma in 2 cases, including one case chronic subdural hematoma following subcortical hematoma five years later.<BR>Surgical management was performed upon discontinuing and neutralyzing warfarin by Vitamin K at that period of diagnosis, raising thromb-test over 50%. The interval of discontinuing warfarin was 1-3 weeks postoperatively, examining blood coagulating system and no case had bleeding tendency nor cerebral embolus except for one case with a bleeding episode postoperatively.<BR>Management of intracranial hemorrhage occured during long-term anticoagulant drug therapy, including chronic subdural hematoma and subcortical hematoma which indicate good prognosis, should be carried out surgically, discontinuing, neutralyzing anticoagulant drug and controlling blood coagulating factors.

• 一般社団法人 日本脳卒中学会の論文

著者

• 鰐渕 博

  埼玉県済生会栗橋病院脳神経外科

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• Intracranial hemorrhage and oral anticoagulant drug therapy.

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