上顎歯肉に発生したmucous membrane plasmacytosisの1例

概要

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Mucous membrane plasmacytosis is an unusual non-neoplastic condition involving plasma cell proliferation. The precise etiology, pathogenesis, and treatment of the lesions are unknown. A case of mucous membrane plasmacytosis in the left upper gingiva of a 60-year-old Japanese man is presented. The patient visited our clinic because of a reddish swelling in the left upper molar gingiva. The general history suggested gingival hypertrophy caused by long-term treatment with nifedipine. Gingivectomy was performed with the patient under local anesthesia. Histopathologically, the lesion showed dense infiltration of plasma cells without cellular atypia in the submucosa. Immunohistochemical studies for kappa and lamda light chains showed positive staining, indicating polyclonality. The final diagnosis was therefore mucous membrane plasmacytosis. There was no evidence of recurrence 1 year after excision.
Japanese Society of Oral and Maxillofacial Surgeonsの論文