Impact of Cardiac Rehabilitation on Renal Function in Patients With and Without Chronic Kidney Disease After Acute Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
Background: Although there is a general fear that exercise training might deteriorate renal function in chronic kidney disease (CKD) patients, the effect of cardiac rehabilitation (CR) on renal function in acute myocardial infarction (AMI) patients with CKD remains unknown. We sought to determine whether CR is associated with amelioration or deterioration of renal function in such patients. Methods and Results: We enrolled 528 AMI patients who participated in a 3-month CR program. Clinical data before and after CR were compared according to participation in CR and comorbidities. In patients without CKD (estimated glomerular filtration rate [eGFR] ≥60ml·min−1·1.73m−2, n=348), peak oxygen uptake (VO2) and B-type natriuretic peptide (BNP) improved without a change in eGFR. In contrast, in patients with CKD (eGFR <60ml·min−1·1.73m−2, n=180), eGFR improved (48±12 to 53±15ml·min−1·1.73m−2, P<0.001), together with improvements in peak VO2 and BNP. When patients with CKD were divided into non-active (≤1time/week, n=70) and active participants (≥1.1time/week, n=110) according to attendance in CR, active participants showed an improvement in eGFR (50±10 to 53±13ml·min−1·1.73m−2, P<0.001), whereas eGFR did not change in non-active participants. Similar results were obtained in each subgroup of patients with hypertension, dyslipidemia, or diabetes mellitus. Conclusions: In AMI patients with CKD, active participation in CR was associated with improved peak VO2, BNP, and eGFR.
- 一般社団法人 日本循環器学会の論文
著者
-
Noguchi Teruo
Department Of Cardiology National Cardio Vascular Center
-
Nakanishi Michio
Department Of Cardiology Kokura Memorial Hospital
-
Ohara Takahiro
Department Of Cardiology National Cardiovascular Center
-
Yanase Masanobu
Department Of Cardiology Nagoya University Graduate School Of Medicine
-
Kumasaka Reon
Department Of Cardiology Kameda Medical Center
-
Arakawa Tetsuo
Department Of Gastroenterology Graduate School Of Medicine Osaka City University Medical School
-
Takaya Yoichi
Department Of Cardiology Okayama University Graduate School Of Medicine Dentistry And Pharmaceutical
-
Goto Yoichi
Department Of Cardiology National Cardiovascular Center
-
Takaki Hiroshi
Department of Agriculture and Forest Science, Faculty of Agriculture, Miyazaki University
-
Nakanishi Michio
Departments of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
-
Noguchi Teruo
Departments of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
-
Kawano Yuhei
Hypertension and Nephrology, National Cerebral and Cardiovascular Center
-
Yanase Masanobu
Departments of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
-
Goto Yoichi
Departments of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
-
Takaki Hiroshi
Departments of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
関連論文
- Experience of appendicular thermal therapy applied to a patient with a left ventricular assist device awaiting heart transplantation
- FRS-007 Functional inhibition of p300 in the post-natal heart leads to mitochondrial dysfunction and cell death in mice(Novel Pathophysiological Mechanisms of Heart Failure(M),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Ci
- PE-441 Essential Role of p300 in Post-natal Cardiac Mitochondrial Gene Expression and Maintenance of Normal Cardiac Function(Heart failure, basic-5, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-651 Predictors of the Improvement in Left Ventricular Ejection Fraction in Non-Ischemic Dilated Cardiomyopathy during Beta-Blocker Therapy(PJ109,Heart Failure (Treatment) 3 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanes
- PJ-504 Aortic Pulse Wave Velocity can Predict Left Ventricular Diastolic Dysfunction in a Community-based Population(PJ085,Heart Failure (Pathophysiology) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PE-357 Does Preoperative Left Atrial Dilatation Predict Adverse Events after Aortic Valve Replacement?(PE060,Valvular Heart Disease (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-254 "Cardiac Anemia" is an Independent Predictor of Prognosis in Patients with Non-Ischemic Chronic Heart Failure(PE043,Heart Failure (Biomarker) 1 (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-034 Negative Impact of Cardio-renal Anemia Syndrome on Beta-blocker Tolerance and Subsequent Major Adverse Cardiac Events in Chronic Heart Failure(PE006,Kidney/Renal Circulation/CKD 1 (H),Poster Session (English),The 73rd Annual Scientific Meeting of T
- OJ-141 Relationship between Aortic Valve Area and Pressure Gradient : Impact of Transvalvular Flow Rate on Assessment of Aortic Stenosis(OJ24,Echo/Doppler (Others) (I),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circula
- 2 Present Strategy for the Treatment of Profound Heart Failure : Long-term Support by Left Ventricular Assist Systems and Heart Transplantation(Therapeutic Strategy for Severe Heart Failure-From LVAD to Heart Transplantation-,Symposium 11 (SY-11) (H),The
- Plasma Adiponectin Is Associated with Plasma Brain Natriuretic Peptide and Cardiac Function in Healthy Subjects
- OE-352 The Preoperative Cardio-Renal-Anemia-Syndrome and Myocardial Fibrosis Have Negative Impact on Survival and Myocardial Recovery After Left Ventricular Assist Device Implantation(Heart failure, clinical(04)(M),Oral Presentation(English),The 72nd Annu
- PJ-504 Aortic Pulse Wave Velocity can Predict Left Ventricular Diastolic Dysfunction in a Community-based Population(PJ085,Heart Failure (Pathophysiology) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PJ-745 Clinical Usefulness of the Non-invasive Stroke Volume Measurement System, the Task Force[○!R] Monitor, in Patients with Pulmonary Hypertension(Pulmonary circulation(04)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese
- PJ-015 Novel SCN5A Mutations Associated with Japanese Brugada Syndrome Patients(Arrhythmia, basic(04)(A),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Hemodynamic and Echocardiographic Evaluation of Orthotopic Heart Transplantation With the Modified Bicaval Anastomosis Technique
- 2 Present Strategy for the Treatment of Profound Heart Failure : Long-term Support by Left Ventricular Assist Systems and Heart Transplantation(Therapeutic Strategy for Severe Heart Failure-From LVAD to Heart Transplantation-,Symposium 11 (SY-11) (H),The
- OE-352 The Preoperative Cardio-Renal-Anemia-Syndrome and Myocardial Fibrosis Have Negative Impact on Survival and Myocardial Recovery After Left Ventricular Assist Device Implantation(Heart failure, clinical(04)(M),Oral Presentation(English),The 72nd Annu
- 4 Cardiac rehabilitation in the management of patients with end-stage heart failure(Symposium 16 (SY-16) (H) Cardiac Rehabilitation : Innovative Approach to Improve Patient Care,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulatio
- 4 Long-term Use of Left Ventricular Assist System as a Bridge to Heart Transplant : Superior Survival Rate to REMATCH Trial(Symposium 8 (SY-08) (M) New Strategies for Management of Severe Heart Failure with New Devices and Surgery,Special Program,The 72nd
- PJ-184 Effects of Cardiac Rehabilitation in Patients with Non-Diabetic, Glucose Intorelance and Diabetic and after Acute Myocardial Infarction(Exercise test/Cardiac rehabilitation-4 (IHD) PJ31,Poster Session (Japanese),The 70th Anniversary Annual Scientif
- PJ-182 Beta-blocking Agents Therapy does not Hinder the Beneficial Effects of Cardiac Rehabilitation in Patients with Acute Myocardial Infarction(Exercise test/Cardiac rehabilitation-4 (IHD) PJ31,Poster Session (Japanese),The 70th Anniversary Annual Scien
- OJ-150 Mechanisms of Reduced Exercise Capacity in Diabetic Patients with Acute Myocardial Infarction : Chronotoropic Incompetence and Glycemic Dysregulation(Exercise test/Cardiac rehabilitation-1 (IHD) OJ25,Oral Presentation (Japanese),The 70th Anniversar
- PJ-452 The Presence of Previous Cerebral Infarction in Vertebrobasilar System may Exacerbate Ventilatory Oscillations during Exercise in Patients with Heart Failure(PJ076,Exercise Test/Cardiac Rehabilitation 1 (H),Poster Session (Japanese),The 73rd Annual
- PE-507 Slower Periodic VO_2 Oscillations during Exercise Indicate Poorer Prognosis of Patients with Heart Failure(PE085,Exercise Test/Cardiac Rehabilitation (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Societ
- OE-261 Abnormal Ventilatory and Oxygen Kinetics to Exercise in Patients with Arteriosclerosis Obliterans (ASO)(OE44,Exercise Test/Cardiac Rehabilitation (H),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society
- PJ-869 Is the Extent of Exercise VO2 Oscillations Related to the Severity of Heart Failure?(Exercise test / Cardiac rehabilitation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-868 Exercise May Exert as a Trigger to Magnify the Preexisting Oscillation at Rest(Exercise test / Cardiac rehabilitation(08)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-101 Incidence and Clinical Characteristics of Exercise VO2 Oscillations: A Single-Center Experience from 4792 Consecutive Exercise Tests(Exercise test/Cardiac rehabilitation(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japa
- PJ-100 Exercise Ventilatory Oscillations Disappear during Intense Exercise, Which is Temporally Coincident with the Disappearance of Lag-Time between VE and ETCO2(Exercise test/Cardiac rehabilitation(05)(H),Poster Session(Japanese),The 72nd Annual Scienti
- OE-178 Slower Periodic VO2 Oscillations during Exercise Indicate Worse Clinical Status of Patients with Heart Failure(Exercise test/Cardiac rehabilitation(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
- 3 Human Atrial Natriuretic Peptide and Nicorandil as an Adjunct to Reperfusion Therapy for Acute Myocardial Infarction : Lessons from J-WIND Trials(Discovery of Adjunctive Therapies for Acute Myocardial Infarction-From Bench to Bedside-, The 71st Annual S
- Myocardial Invasion of Cardiac Lymphoma Assessed With Myocardial Strain Imaging
- PE-365 Isoproterenol Terminates Atrial Fibrillation : Possible Electrophysiological Mechanism Compared with Class 1 Antiarrhythmic Drug(Arrhythmia, diagnosis/Pathophysiology/EPS(08)(A),Poster Session(English),The 72nd Annual Scientific Meeting of the Japa
- DPJ-054 Is Cardiac Rehabilitation Unnecessary in Low Prognostic Risk Patients with Acute Myocardial Infarction in the Primary Intervention Era?(DPJ09,Exercise Test/Cardiac Rehabilitation (H),Digital Poster Session (Japanese),The 73rd Annual Scientific Mee
- PJ-503 14-year Trends of Participation Rate in Cardiac Rehabilitation after Acute Myocardial Infarction : Impact of Age and Gender(Exercise test/Cardiac rehabilitation(07)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
- PJ-196 Clinical Features of Post-Myocardial Infarction Patients with Elevated B-Type Natriuretic Peptide Level Despite Preserved Ejection Fraction(Acute myocardial infarction, clinical (diagnosis/treatment)(09)(IHD),Poster Session(Japanese),The 72nd Annua
- PJ-120 Differing Mechanisms of Improvement in Plasma BNP between Patients with Systolic versus Diastolic Dysfunction after Acute Myocardial Infarction(Heart failure, clinical(13)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japane
- PE-311 Influence of Metabolic Syndrome Risk Factors on Left Ventricular Diastolic Dysfunction : Assessed with Left Atrial Size and Tissue Doppler Imaging(Diabetes/Obesity/Metabolic syndrome(06)(H),Poster Session(English),The 72nd Annual Scientific Meeting
- PJ-515 Plasma matrix metalloproteinase (MMP)-2 level is associated with left ventricular remodeling in congestive heart failure(Heart Failure, Clinical 14 (M) : PJ86)(Poster Session (Japanese))
- PE-167 Association of serum Insulin-like growth factor 1, as the Marker of Severity of Acute Heart Failure, with Inflammatory Responses(Heart Failure, Clinical 5 (M) : PE29)(Poster Session (English))
- PJ-522 Dynamic Study of Myocardial Gd-enhancement by Magnetic Ressonance Imaging in Stunned Myocardium(MRI/MRA-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-679 Clinical Significance of High Molecular Weight Form of Adiponectin in Male Patients with Coronary Artery Disease(Diabetes / Obesity / Metabolic syndrome(14)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
- OE-042 Exercise Cardiac Rehabilitation Improves Exercise Capacity in Patients weaned from Left Ventricular Assist Device after Recovery from Severe Heart Failure(Exercise Test/Cardiac Rehabilitation 1 (IHD) : OE6)(Oral Presentation (English))
- PE-589 Paradoxically Low-flow, Low-gradient Severe Aortic Stenosis Despite Preserved Contraction : Its Prevalence and Clinical Characteristics.(Valvular heart disease/Pericarditis/Cardiac tumor(02)(M),Poster Session(English),The 72nd Annual Scientific Mee
- PE-193 Three-years Experience of Transvenous Pacemaker Lead Removals Using Electrosurgical Dissection System (EDS)(PE033,Arrhythmia, Others (Clinical/Diagnosis/Treatment) 3 (A),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Ci
- Impact of End Stage Renal Disease on Outcomes After Rotational Atherectomy (Rotablator)
- FRS-117 MRI Delayed Hyperenhancement Overestimates Acute Myocardial Infarction Size(Nuclear Cardiology (I) : FRS14)(Featured Research Session (English))
- The Ratio of Brain Natriuretic Peptide to Left Ventricular End-diastolic Volume as a Potential Index of Myocardial Viability (Old Myocardial Infarction/Remodeling 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PE-369 There is a Possibility that Quitting Smoking does not Contribute to Prognostic Improvement in VAP Patient without Signigicant Coronary Narrowing(Smoking, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-376 Normal Coronary Angiogram Suggests Better Prognosis of Patients with Variant Angina Pectoris(Angina pectoris, basic/clinical-1, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Insulin Resistance and Fasting Hyperinsulinemia Are Risk Factors for New Cardiovascular Events in Patients With Prior Coronary Artery Disease and Normal Glucose Tolerance
- Myocardial Ischemia During Percutaneous Transluminal Coronary Angioplasty in Patients With Rich Collateral Circulation of the Target Lesion
- Association of CT Dinucleotide Repeat Polymorphism in the 5'-Flanking Region of the Guanylyl Cyclase (GC)-A Gene with Essential Hypertension in the Japanese
- Genetic Disruption of Angiotensin II Type 1a Receptor Improves Long-Term Survival of Mice With Chronic Severe Aortic Regurgitation
- PJ-377 Delayed Improvement of the Left Ventricular Dyssynchrony after Cardiac Resynchronization Therapy in Severe Chronic Heart Failure(Heart failure, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-085 Bepridil Magnifies Left-to-Right Atrial Frequency Gradient in Chronic Atrial Fibrillation(ECG/Body surface potential mapping/Holter-6, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-542 Cystatin C indicates diastoric dysfunction in patients without clinical cardiac dysfunction(Heart failure, clinical(12)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Diabetes Mellitus Attenuates the Improvement in Baroreflex Sensitivity in Patients after Acute Myocardial Infarction Participating in Exercise Cardiac Rehabilitation
- In-Vivo Electrophysiological Study in Dominant-Negative NRSF Transgenic Mice : Ventricular Arrhythmia Vulnerability and Sudden Cardiac Death
- Thin Filament Based Modulation of Contractile Performance in Human Heart Failure : A Potential Role of PKC Mediated Phosphorylation
- Myosin from Failing and Non-Failing Human Ventricles Exhibit Similar Contractile Properties
- OE-216 Obesity Paradox in Japanese Heart Failure Patients : Impact of BMI on the Prognosis of Acute Decompensated Heart Failure(Heart failure, clinical(03)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Societ
- OE-124 Impact of Acute Phase Plasma BNP Levels on the Post-Discharge Long-Term Prognosis in Patients with Acute Decompensated Heart Failure(Heart failure, clinical(02)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circul
- PE-419 Characteristics of Late Gadolinium Enhancement on CMR in Histologically Proven Cardiac Sarcoidosis and Idiopathic Dilated Cardiomyopathy(PE070,CT/MRI (Myocardium) (I),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circu
- Angiotensin II-Induced Ventricular Hypertrophy and Extracellular Signal-Regulated Kinase Activation Are Suppressed in Mice Overexpressing Brain Natriuretic Peptide in Circulation
- OJ-021 Blockade of T-type Calcium Channel Reduced the Arrythmogenicity in the Dominant Negative NRSF Transgenic Mice(Heart failure, basic-2 (M) OJ4,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Soc
- SOCS1/JAB Likely Mediates the Protective Effect of Cardiotrophin-1 Against Lipopolysaccharide-Induced Left Ventricular Dysfunction In Vivo
- Overexpression of Brain Natriuretic Paptide Attenuates Cardiac Remodeling after Myocardial Infarction in Mice(Old Myocardial Infarction/Remodeling 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-622 Significance of a novel interaction between NRSF and classII HDAC involved in the induction of ANP gene expression by Endothelin-1(Cardiac Hypertrophy, Basic and Clinical 2 (M) : PJ104)(Poster Session (Japanese))
- OJ-481 Beneficial Effects of Brain Natriuretic Peptide Overexpression in Cardiac Remodeling after Myocardial Infarction in Mice(Old Myocardial Infarction/Remodeling 1 (IHD) : OJ59)(Oral Presentation (Japanese))
- Role of Renin-Anglotensin System in Cardiac Remodeling after Aortic Regurgitation in Mice
- ERK5 Plays a Critical Role in Cardiotrophin-1-Induced Hypertrophy of Neonatal Rat Ventricular Myocytes
- Evidence for Cardiac Myocyte Regeneration in Injured Myocardium by Bone Marrow Derived Cells
- JAB/SOCS1 and CIS3/SOCS3 inhibit hypertrophic response to cardiotrophin-1 independent of STAT3 suppression in neonatal rat ventricular myocytes
- Overxepression of brain natriuretic peptide mediates cardiac matrix metalloproteinase induction and induces cardiac rupture after acute myocardial infarction in mice
- Inhibition of histone deacetylase selectively induces expression of cardiac embryonic genes that contain neuron-restrictive silencer element in cultured ventricular myocytes
- Disruption of natriuretic peptides receptor A leads to higher mortality and exaggerated left ventricular remodeling after myocardial infarction in mice
- Genetic disruption of angiotensin II type 2 (AT2) receptor worsened short-term survival after acute myocardial infarction in mice
- Accelerated Progression and Morbidity in Patients With Aortic Stenosis on Chronic Dialysis
- PE-565 Plasma Endothelin-1 Concentration in Patients with Pulmonary Hypertension Treated with Bosentan(Pulmonary circulation(02)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Second Left Ventricular Aneurysm Newly Developed in a Patient With Untreated Cardiac Sarcoidosis
- Assessment of Plasma miRNAs in Congestive Heart Failure
- Impact of Age on the Effect of Cardiac Rehabilitation after Acute Myocardial Infarction : Do Elderly Patients Gain Less Benefit?
- Improving Excess Ventilation by Exercise Cardiac Rehabilitation after Acute Myocardial Infarction : Which Patient Benefits?
- Impact of Exercise Intensity on Left Ventricular Function and Neurohumoral Factors after Acute Myocardial Infarction : A Prospective Randomized Study
- Improvement in Ventilatory Efficiency after Exercise Training Combined with Beta-Adrenergic Blocker Therapy in Patients with Dilated Cardiomyopathy
- Increased Inflammatory Markers in Patients with Vasospastic Angina
- Exercise Cardiac Rehabilitation Improves Exercise Capacity in Patients with Left Ventricular Assist Device (LVAS)
- Efficacy of Out-Patient Cardiac Rehabilitation in Low Prognostic Risk Patients After Acute Myocardial Infarction in Primary Intervention Era
- Impact of Preoperative Percutaneous Cardiopulmonary Support on Outcome Following Left Ventricular Assist Device Implantation
- Myocardial Impairment Detected by Late Gadolinium Enhancement in Hypertrophic Cardiomyopathy: Comparison with 99mTc-MIBI/Tetrofosmin and 123I-BMIPP SPECT
- MicroRNA 210 as a Biomarker for Congestive Heart Failure
- Detection of Intramural Hematoma and Serial Non-Contrast T1-Weighted Magnetic Resonance Imaging Findings in a Female Patient With Spontaneous Coronary Artery Dissection
- Detection of High-Risk Atherosclerotic Plaques by Magnetic Resonance Imaging
- Exercise-Induced ST Elevation in Patients With Non-Ischemic Dilated Cardiomyopathy and Narrow QRS Complexes:– Novel Predictor of Long-Term Prognosis From Exercise Testing –
- Impact of Cardiac Rehabilitation on Renal Function in Patients With and Without Chronic Kidney Disease After Acute Myocardial Infarction
- Exercise-Induced ST Elevation in Patients With Non-Ischemic Dilated Cardiomyopathy and Narrow QRS Complexes : Novel Predictor of Long-Term Prognosis From Exercise Testing
- Detection of High-Risk Atherosclerotic Plaques by Magnetic Resonance Imaging
- Targeting of High Peak Respiratory Exchange Ratio Is Safe and Enhances the Prognostic Power of Peak Oxygen Uptake for Heart Failure Patients