Application of Accelerated Plethysmography for Measuring Pulse Wave Velocity
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In the present study, accelerated plethysmography (APG) obtained through a small near-infrared radiation sensor was used to measure pulse wave velocity (PWV). This study included 51 asymptomatic participants (aged 21–90 years), who were assigned to 3 groups : young (n=14), middle-aged (n=21), and older (n=17). Pulse transmission times (PTT) were determined using electrocardiography (ECG) and APG in the head, finger, and plantar. The measuring distances were estimated using tape measure over the body surface. PWV was calculated for each segment as the measuring distance divided by the corresponding PTT. To confirm the accuracy of the PTT obtained from ECG and APG, twelve of 51 participants had PTT measured by previous methods. The PTT obtained from ECG and APG was significantly correlated with the PTT obtained from previous methods (Pearsons correlation, P<0.001). The PWV including the abdominal aortic systems (heart-plantar PWV, head-plantar PWV, and finger-plantar PWV) significantly increased with age (analysis of variance, P<0.001 ; single liner regression, P<0.001). However, the PWV not including the abdominal aortic systems (heart-head PWV, heart-finger PWV, and head-finger PWV) were not affected by age. After the multiple regression analysis controlling for age, sex, height, BMI, R-R interval, systolic blood pressure and diastolic blood pressure, relationships between the PWV including the abdominal aortic systems and age were still significant (multiple regression analysis, P<0.001). These tendencies were similar to those observed in previous studies and agree with the elastic and muscular artery properties. Although the measurement of PWV using the methods employed in the present study is simple and rapid compared to the previous methods, the methods of present study compares favorably with the previous methods for the measurement of PWV.
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