Inhibitory effect of coated mannan against the adhesion of Candida biofilms to denture base resin
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概要
- 論文の詳細を見る
The adherence of Candida on dentures is related to diseases such as denture stomatitis and aspiration pneumonia. Mannan is a major component of the Candida cell surface, and contributes to the cell adherence. A previous report indicated that the adherence of C. albicans to culture dishes was inhibited by the coating them with mannan. The purpose of this study was to examine the adhesion inhibitory effect of mannan coating on acrylic denture surfaces against C. albicans and C. glabrata. The amount of Candida attached on the acrylic surfaces coated with mannan was calibrated by culture methods. Mannan showed significant inhibitory effects on Candida adhesion in both the yeast and hyphal form in a concentration-dependent manner, and the durability of the inhibitory effect continued for three days. These results suggest that mannan coating on the denture base acrylic can prevent Candida adhesion on the denture.
著者
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OHKUBO Chikahiro
Department of Removable Prosthodontics, Tsurumi University School of Dental Medicine
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MAEDA Nobuko
Department of Bacteriology, School of Dental Medicine, Tsurumi University
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Sato Maki
Department Of Dermatology Tohoku University School Of Medicine
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Ohshima Tomoko
Department Of Oral Bacteriology School Of Dental Medicine Tsurumi University
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Ohkubo Chikahiro
Department Of Removable Prosthodontics School Of Dental Medicine Tsurumi University
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