Vaporizing Thrombus With Excimer Laser Before Coronary Stenting Improves Myocardial Reperfusion in Acute Coronary Syndrome
スポンサーリンク
概要
- 論文の詳細を見る
Background: Mechanical reperfusion has proven to be an unquestionably superior treatment strategy over that of thrombolytic therapy in patients with acute coronary syndrome (ACS). Excimer laser coronary angioplasty (ELCA) is a unique revascularization device that has a lytic effect on thrombus, in addition to its debulking effect on the atherosclerotic plaque beneath the thrombus. Methods and Results: This single-center retrospective analysis consisted of consecutive ACS patients treated with ELCA (n=50) and age- and sex-matched ACS patients treated with manual aspiration (n=48) without use of a distal protection device. Success rate was judged by lesion crossability, procedure complications, and significant reduction of stenosis. Tissue-level perfusion was assessed on antegrade Thrombolysis In Myocardial Infarction (TIMI) flow grade, myocardial blush grade (MBG), and ST-segment elevation resolution (STR). Short-term outcome was evaluated according to occurrence of in-hospital major adverse cardiac events (MACE; myocardial infarction, target lesion revascularization, coronary artery bypass graft, and death). Lesion crossability was higher in the ELCA group than in the aspiration group (96.2% vs. 82.6%, P=0.04). Attainment of TIMI 3 flow (86.0% vs. 68.8%, P=0.04) and MBG 3 (76.0% vs. 54.2%, P=0.02) was also higher in the ELCA group than in the aspiration group. Complete STR was similar between the 2 groups. In-hospital MACE were significantly more frequent in the aspiration group. Conclusions: ELCA is feasible, safe, and effective for the treatment of patients with ACS and appears to be useful as an adjunctive lesion preparation device. (Circ J 2013; 77: 1445–1452)
著者
-
Asano Katsuaki
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Takiuchi Shin
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Hanafusa Toshiaki
First Department Of Internal Medicine Osaka Medical College
-
Yabuki Masanori
Department of Cardiology, Higashi Takarazuka Satoh Hospital
-
Otsuji Satoru
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
-
Ikushima Masashi
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Yabuki Masanori
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Higashino Yorihiko
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Fukumoto Atsushi
Department Of Artificial Intelligence Kyushu Institute Of Technology:(present Address) Canon Inc.
-
Hasegawa Katsuyuki
Department Of Cardiology Higashi Takarazuka Satoh Hospital
-
Fukumoto Atsushi
Department of Cardiology, Higashi takarazuka satoh hospital
-
Ikushima Masashi
Department of Cardiology, Higashi takarazuka satoh hospital
-
Takiuchi Shin
Department of Cardiology, Higashi takarazuka satoh hospital
-
Asano Katsuaki
Department of Cardiology, Higashi takarazuka satoh hospital
-
Kashiyama Toshikazu
Department of Cardiology, Higashi Takarazuka Satoh Hospital
-
Shishikura Daisuke
Department of Cardiology, Higashi Takarazuka Satoh Hospital
-
Yasuda Tokuki
Department of Cardiology, Higashi Takarazuka Satoh Hospital
関連論文
- PJ-649 Effect of Noninvasive Positive Pressure Ventilation (NPPV) on the Clinical Course in Our Hospital(PJ109,Heart Failure (Treatment) 3 (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Impact of Myocardial Angiotensin-Converting Enzyme Activity on Coronary Vascular Resistance and Serum Brain Natriuretic Peptide Concentration in Coronary Bypass Surgery
- INSIG2 gene rs7566605 polymorphism is associated with severe obesity in Japanese
- Variations in the FTO gene are associated with severe obesity in the Japanese
- Hypertension Attenuates the Efficacy of Hypoglycemic Therapy for Preserving Coronary Flow Reserve in Patients with Type 2 Diabetes
- PE-354 Aortic Valve Thickness Depends on Cardiac ACE Activity, not Blood Pressure in 1K-, 1K1C-, and 2K1C-Rabbit Models(PE060,Valvular Heart Disease (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- DPJ-036 Area with High Strain is Susceptible to Lesion Formation in Aortic Valve(DPJ06,Valvular Heart Disease/Pericarditis/Cardiac Tumor (M),Digital Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-244 Protruding Atheroma in the Thoracic Aorta Detected by Multislice Computed Tomography Can Predict the Major Vascular Events(OE42,CT/MRI (Coronary/Vascular) 2 (I),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulat
- OE-235 Evidence of Plaque Neovascularization and Effects of Angiotensin Receptor Blocker in Cholesterol-Fed Monkey(OE40,Atherosclerosis, Basic 2 (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PE-441 Virtual Histology Assessment of Attenuation Image Detected With 40MHz Gray-scale IVUS
- ACE2 Mutant Mice Increase Cardiac Angiotensin II and Increase Incidence of Heart Failure in Response to Pressure Overload (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Spectral-Lag Relations in GRB Pulses Detected with HETE-2
- Carotid Intima-Media Thickness Is Correlated with Impairment of Coronary Flow Reserve in Hypertensive Patients without Coronary Artery Disease
- Efficacy of hochuekkito for postprandial hypotension complicated by diabetes
- Association between senescence-related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects : The Tanno and Sobetsu study
- Successful treatment of thrombotic thrombocytopenic purpura with repeated plasma exchange in a patient with microscopic polyangitis
- Association of Polymorphism in the Promoter Region of the Apolipoprotein E Gene with Diastolic Blood Pressure in Normotensive Japanese
- Serum Heart-Type Fatty Acid-Binding Protein Concentration Positively Correlates With the Length of Aortic Dissection
- Serum protein profile of rheumatoid arthritis treated with anti-TNF therapy (infliximab)
- Information Extraction from Personal Computer Specifications on the Web Using a User's Request (Databases)
- A SECOND COMPONENT OF HLA-LINKED SUSCEPTIBILITY TO TYPE 1 DIABETES MAPS TO CLASS I REGION
- MOLECULAR SCANNING OF THE HUMAN IL-21 GENE AND ASSOCIATION STUDY WITH TYPE 1 DIABETES
- Simple and Useful Tests for Discriminating Between Acute Aortic Dissection of the Ascending Aorta and Acute Myocardial Infarction in the Emergency Setting
- PJ-542 Long-term Clinical Outcomes of Patients Treated with Multiple Sirolimus-Eluting Stents in Multivessel Coronary Artery Lesions(PJ091,Coronary Revascularization, PCI (DES) 3 (IHD),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Ja
- PE-159 Alternations in Rotational Mechanics of Failured Heart and the Prediction of Mid Term Response to Cardiac Resynchronization Therapy (CRT)(PE027,CRT (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-452 Acute and mid-term results of Sirolimus-eluting stents (SES) following rotational atherectomy (RA) in patients with heavily calcified coronary lesions(Coronary revascularization, PCI(21)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meet
- PJ-445 Immediate and mid-term outcomes of Sirolimus-eluting stent (SES) implantation for chronic total occlusions(Coronary revascularization, PCI(20)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-051 Clinical and angiographical results after durg-eluting stents implantation in the left main true bifurcation lesion.(Coronary revascularization, PCI(07)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Soc
- PE-478 What is the Predictor of Adverse Events for the Patients Treated with Cypher Stents?(Coronary revascularization, PCI-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-669 Feasibility and Safety of Directional Coronary Atherectomy Followed by Sirolimus-eluting Stent Implantation for the Treatment of In-stent Restenosis(Coronary revascularization, PCI-21 (IHD) PJ112,Poster Session (Japanese),The 70th Anniversary Annua
- OE-313 Ten-year Follow-up after Percutaneous Coronary Intervention in Unprotected Left Main Coronary Artery(Coronary revascularization, PCI-3 (IHD) OE53,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- OE-053 Does Switching to More Aggressive Statin Bring Beneficial Effect beyond Lipid Lowering Effect?(Atherosclerosis, Clinical 1 (IHD) : OE7)(Oral Presentation (English))
- Usability of the NFW Galaxy Profile as a Cosmological Tool Estimated from 2-Image Gravitational Lens Systems
- PE-293 Single polymorphism of Lipocalin-type prostaglandin D synthase gene is associated with HDL-cholesterol levels and carotid plaques in hypertensive patients(Heart Failure, Clinical 11 (M) : PE50)(Poster Session (English))
- N-Glycan fucosylation of epidermal growth factor receptor modulates receptor activity and sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor
- FULMINANT TYPE 1 DIABETES : OVERVIEW
- Fulminant Type 1 Diabetes Mellitus
- Successful Catheter Interventional Therapy for Acute Coronary Syndrome Secondary to Kawasaki Disease in Young Adults
- Trapidil increases plaque stability without lipid-lowering effect in rabbit plaque model
- Analysis of In-hospital Death After Percutaneous Coronary Intervention for Chronic Total Occlusion (Coronary Revascularization, PTCA/Stent/DCA/Rotablator/New Device 15 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Investigation of Ultra-late In-stent Restenosis(Restenosis after Angioplasty, Basic/Clinical 5 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-302 Histopathological Characteristics of Edge Restenosis Following Intracoronary Brachytherapy for In-Stent Restenosis(Restenosis after Angioplasty, Basic/Clinical 2 (IHD) : OJ36)(Oral Presentation (Japanese))
- OJ-117 Percutaneous Coronary Intervention for Unstable Angina in Unprotected Left Main Coronary Artery(Coronary Revascularization, PICA/Stent/DCA/Rotablator/New Device 2 (IHD) : OJ14)(Oral Presentation (Japanese))
- Klotho gene delivery suppresses oxidative stress in vivo
- Photon Emission in a Cascade from Relativistic Protons Initiated by Residual Thermal Photons in Gamma-Ray Bursts
- Elliptical Lens Model in PG 1115+080
- Role of Plaque Proliferation in Late Lumen Loss After Directional Coronary Atherectomy
- Percutaneous Revascularization of Lesions With Saphenous Vein Graft Failure : Influence of Chronic Total Occlusion on Early Outcome
- Serum Concentrations of Granulocyte Colony-Stimulating Factor (G-CSF) in Antithyroid Drug-Induced Agranulocytosis
- Dispersion of the Break Energy in the GRB Internal Shock Model
- Intracellular Ca^-elevation Plays a Crucial Role in the PKC-independent Antagonizing Effect of Angiotensinll against Insulin-induced Production of PI(3, 4, 5)P3 in Cardiomyocytes (Molecular Biology, Myocardium 2 (M), The 69th Annual Scientific Meeting
- Large Third-Order Nonlinear Optical Susceptibilities of Multiply-Bonded M_2(pyphos)_4 and M_2Pd_2Cl_2(pyphos)_4(M=Cr, Mo ; Pyphos=6-Diphenylphosphino-2-pyridonate) by Picosecond Degenerate Four-Wave Mixing Method
- Immunohistochemical Findings of Ruptured-abdominal Aortic Aneurysm and Acute Aortic Dissection(Atherosclerosis, Clinical 6 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- HMG-CoA Reductase Inhibitors Suppress Myosin Light Chain Phosphorylation in Cultured Smooth Muscle Cell
- Transluminal Percutaneous Septal Myocardial Ablation in a Patient With Hypertrophic Obstructive Cardiomyopathy
- OE-357 GATA-4 is required for cardiac morphogenesis through transactivation of N-cadherin gene(Development and Differentiation 2 (H) : OE45)(Oral Presentation (English))
- OE-356 Novel Transmembrane Type Class VI Semaphorin, Sema6D Regulates Cardiac Morphogenesis Through PlexinA1(Development and Differentiation 2 (H) : OE45)(Oral Presentation (English))
- Preparation of a High Mobility Thin Film of Cd_3As_2
- ANTIARRHYTHMIC EFFECTS OF EICOSAPENTAENOIC ACID DURING MYOCARDIAL INFARCTION : Enhanced Cardiac Microsomal(Ca^-Mg^)-ATPase Activity
- HIGHLY PURIFIED EICOSAPENTAENOIC ACID ATTENUATES TISSUE DAMAGE IN EXPERIMENTAL MYOCARDIAL INFARCTION
- Expression of Toll-like Receptors in the Pancreas of Recent-onset Fulminant Type 1 Diabetes
- Expression of chemokines, CXC chemokine ligand 10 (CXCL10) and CXCR3 in the inflamed islets of patients with recent-onset autoimmune type 1 diabetes
- Therapeutic drug monitoring of cyclosporine microemulsion in interstitial pneumonia with dermatomyositis
- FDG-PET/CT of polymyalgia rheumatica
- Klotho protein diminishes endothelial apoptosis and senescence via a mitogen-activated kinase pathway
- Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population
- Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population
- Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome
- Good response to infliximab in a patient with deep vein thrombosis associated with Behcet disease
- Vaporizing Thrombus With Excimer Laser Before Coronary Stenting Improves Myocardial Reperfusion in Acute Coronary Syndrome
- Vascular Behcet's Disease with Coronary Artery Aneurysm
- Effect of L-thyroxine replacement on apolipoprotein B-48 in overt and subclinical hypothyroid patients
- Association of intima-media thickening of carotid artery with genetic polymorphisms of the regulator of G-protein signaling 2 gene in patients with hypertension and in the general population
- Vaporizing Thrombus With Excimer Laser Before Coronary Stenting Improves Myocardial Reperfusion in Acute Coronary Syndrome