Role of Plaque Proliferation in Late Lumen Loss After Directional Coronary Atherectomy
スポンサーリンク
概要
- 論文の詳細を見る
Previous reports suggest that vessel remodeling is the most important factor in late lumen loss in non-stented lesions, but because results of directional coronary atherectomy (DCA) show that increased plaque area (PA) is also important, the aim of this study was to redefine the mechanism of late lumen loss after DCA. One hundred and twenty lesions that underwent DCA with intravascular ultrasound (IVUS) guidance and serial IVUS analysis were studied, and vessel area (VA), lumen area (LA), PA (VA-LA) and corrected values (each value divided by the value of VA pre procedure to correct the vessel size) were analyzed. During follow-up, corrected VA (cVA) decreased by 0.058±0.191, whereas corrected PA (cPA) increased by 0.087±0.159. Though the %PA (PA/VA) after the procedure showed significant negative correlation with the subsequent change in cPA, it did not correlate with the subsequent change in cVA. In conclusions, the mechanism of late lumen loss after DCA consists of both arterial remodeling and plaque proliferation, and the residual %PA after the procedure determines the subsequent lumen loss. With a lower %PA, a change in the PA contributes more to late lumen loss than do changes in VA. With a high %PA, a change in the VA contributes more to late lumen loss.
- 社団法人日本循環器学会の論文
- 2002-03-20
著者
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AWATA Nobuhisa
Department of Cardiology, Osaka Medical Center for Cancer and Cardiovascular Diseases
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Sumitsuji Satoru
Department of Cardiology, Rinku General Medical Center
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Awata Nobuhisa
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Tsuchikane Etsuo
Department of Cardiology, Toyohashi Heart Center
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Tsuchikane Etsuo
Toyohashi heart center
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Sumitsuji Satoru
Department Of Cardiology Rinku General Medical Center
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Sumitsuji Satoru
Department Of Advanced Cardiovascular Therapeutics Osaka University:heart Center Tokushukai Hospital
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Katoh Osamu
Deartment Of Cardiology Toyohashi Heart Center
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Kobayashi Tohru
Department Of Hematology And Oncology Nagoya University Graduate School Of Medicine
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Katoh Osamu
Cardiovascular Center, Kyoto Katsura Hospital
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Tateyama Hitone
Department of Medicine and Geriatrics, Osaka University Medical School
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Tateyama Hitone
Shiga Medical Center For Adults
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Tamai Hideo
Shiga Medical Center
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Kobayashi Tohru
Department Of Cardiovascular Surgery Osaka Medical Center For Cancer And Cardiovascular Diseases
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Tateyama Hitone
Department Of Internal Medicine Osaka Gyomeikan Hospital
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Otsuji Satoru
Department of Cardiology, Osaka Medical Center for Cancer and Cardiovascular Diseases
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Otsuji Satoru
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Katoh Osamu
Cardiovascular Center Kyoto Katsura Hospital
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Katoh Osamu
Cardiology Toyohashi Heart Center
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Tsuchikane Etsuo
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Kobayashi Tohru
Department Of Agricultural Chemistry Faculty Of Agriculture Kobe University
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Tateyama Hitone
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Sumitsuji Satoru
Departmane Of Cardiology Rinku General Hospital
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