Diagnostic Accuracy of 64-Slice Computed Tomography for Detecting Angiographically Significant Coronary Artery Stenosis in an Unseiected Consecutive Patient Population : Comparison With Conventional Invasive Angiography(CLINICAL INVESTIGATION)
スポンサーリンク
概要
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Background Multislice computed tomography (MSCT) is a promising noninvasive method of detecting coronary artery disease (CAD). However, most data have been obtained in selected series of patients. The purpose of the present study was to investigate the accuracy of 64-slice MSCT (64 MSCT) in daily practice, without any patient selection. Methods and Results Using 64-slice MSCT coronary angiography (CTA), 69 consecutive patients, 39 (57%) of whom had previously undergone stent implantation, were evaluated. The mean heart rate during scan was 72beats/min, scan time 13.6s and the amount of contrast media 72mL. The mean time span between invasive coronary angiography (ICAG) and CTA was 6 days. Significant stenosis was defined as a diameter reduction of >50%. Of 966 segments, 884 (92%) were assessable. Compared with ICAG, the sensitivity of CTA to diagnose significant stenosis was 90%, specificity 94%, positive predictive value (PPV) 89% and negative predictive value (NPV) 95%. With regard to 58 stented lesions, the sensitivity, specificity, PPV and NPV were 93%, 96%, 87% and 98%, respectively. On the patient-based analysis, the sensitivity, specificity, PPV and NPV of CTA to detect CAD were 98%, 86%, 98% and 86%, respectively. Eighty-two (8%) segments were not assessable because of irregular rhythm, calcification or tachycardia. Conclusion Sixty-four-MSCT has a high accuracy for the detection of significant CAD in an unselected patient population and therefore can be considered as a valuable noninvasive technique.
- 社団法人日本循環器学会の論文
- 2006-04-20
著者
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SUZUKI Yasuyuki
Department of Physics, Faculty of Science, Niigata University
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Takeda Yoshihiro
Department of Radiological Technology, Graduate School of Health Sciences, Okayama University
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ITO Tatsuya
Department of Hematology and Oncology, Nagoya University Graduate School of Medicine
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Ito Tatsuya
Department Of Cardiology Toyohashi Heart Center
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Terashima Mitsuyasu
Department of Cardiology, Toyohashi Heart Center
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Tanaka Nobuyoshi
Department of Cardiology, Toyohashi Heart Center
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Nasu Kenya
Department of Cardiology, Toyohashi Heart Center
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Ehara Mariko
Department of Cardiology, Toyohashi Heart Center
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Tsuchikane Etsuo
Department of Cardiology, Toyohashi Heart Center
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Katoh Osamu
Department of Cardiology, Toyohashi Heart Center
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Suzuki Takahiko
Department of Cardiology, Toyohashi Heart Center
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Matsubara Tetsuo
Department of Cardiology, Toyohashi Heart Center
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Terashima Mitsuyasu
Toyohashi heart center
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Satoh Koyo
Toyohashi heart center
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Tsuchikane Etsuo
Toyohashi heart center
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Kobayashi Yoshiki
Deartment Of Cardiology Toyohashi Heart Center
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Takeda Yoshihiro
Department Of Cardiology Rinku General Medical Center
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Muramatsu Toshiya
Saiseikai Yokohana-city Eastern Hospital
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Tsuchikane Etsuo
Deartment Of Cardiology Toyohashi Heart Center
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Katoh Osamu
Deartment Of Cardiology Toyohashi Heart Center
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Kinoshita Yoshihisa
Department Of Pediatrics Hiroshima Prefectural Hospital
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Sato Koyo
Cardiovasucular Medicine Toyohashi Heart Center
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Sato Koyo
Department Of Cardiology Toyohashi Heart Center
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Murata Akira
Department Of Cardiology Toyohashi Heart Center
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Suzuki Tomomichi
Department of Cardiology, Toyohashi Heart Center
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Nasu Kenya
Deartment Of Cardiology Toyohashi Heart Center
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Kawai Masato
Department of Radiology, Toyohashi Heart Center
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Takeda Yoshihiro
Toyohashi Heart Center
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Nasu Kennya
Toyohashi Heart Center
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Suzuki Yoriyasu
Department Of Cardiology Toyohashi Heart Center
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Surmely Jean-Francois
Department of Cardiology, Toyohashi Heart Center
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Takeda Yoshihiro
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Takeda Yoshihiro
Departmane Of Cardiology Rinku General Hospital
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Surmely Jean-francois
Department Of Cardiology
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Matsubara Tetsuo
Department Of Cardiology Toyohashi Heart Center
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Suzuki Tomomichi
Department Of Cardiology Ogaki Municipal Hospital
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Itoh Tatsuya
Cardiology Toyohashi Heart Center
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Tanaka Nobuyoshi
Department Of Cardiology Toyohashi Heart Center
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Ehara Mariko
Department Of Cardiology Toyohashi Heart Center
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Murata Akira
Department Of Applied Biological Science Faculty Of Agriculture Saga University
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Suzuki Yasuyuki
Department Of Cardiology Nihon University Surugadai Hospital
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Kawai Masato
Department Of Cardiology Toyohashi Heart Center
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Takeda Yoshihiro
Department Of Cardiology Toyohashi Heart Center
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Kinoshita Yoshihisa
Deartment Of Cardiology Toyohashi Heart Center
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Katoh Osamu
Department Of Cardiology Toyohashi Heart Center
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Katoh Osamu
Cardiovascular Center Kyoto Katsura Hospital
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Kinoshita Yoshihisa
Department Of Cardiology Toyohashi Heart Center
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Suzuki Takahiko
Department Of Applied Medical Engineering Science Yamaguchi University Graduate School Of Medicine
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Inada Tsuyoshi
Department Of Cardiology Toyohashi Heart Center
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Tsuchikane Etsuo
Department Of Cardiology Osaka Medical Center For Cancer And Cardiovascular Diseases
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Terashima Mitsuyasu
Department Of Cardiology Miki City Hospital
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Suzuki Yasuyuki
Department Of Cardiology Toyohashi Heart Center
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Murata Akira
Department Of Agricultural Chemistry Saga University
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Suzuki Yasuyuki
Department Of Biochemistry Kinki University School Of Medicine
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Suzuki Yasuyuki
Department Of Anesthesia And Intensive Care National Center For Child Health And Development
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Suzuki Yasuyuki
Department Of Anesthesia And Icu National Children's Hospital
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Kinoshita Yoshihisa
Department Of Cardiology
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ITO Tatsuya
Department of Antibiotics, Research Institute for Chemobiodynamics, Chiba University
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