Clinical Value of the Measurement of the Uric Acid in CSF in Patients with Cerebral Diseases:Part II. Postoperative Meningitis

概要

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Some studies on the cerebrospinal fluid (CSF) uric acid in patients with various neurological diseases were reported in the literature. In this study we discussed the clinical value of the sequential measurement of the CSF uric acid and CSF cells in patients with postoperative acute meningitis. CSF was investigated for uric acid and cells in 9 cases with postoperative meningitis and 4 cases without that. The results as follows, 1) The CSF uric acid level was increased markedly in direct proportion to neutrophilia in the CSF. 2) Seven cases of the 9 with postoperative meningitis had biphasic pattern patteronf the CSF uric acid level. 3) Four cases without postoperative meningitis had reduced progressively the CSF uric acid level and then they were nor m alized until the fourth day after operation.
Japanese Society of Gout and Nucleic Acid Metabolismの論文