Pancreatitis with Pancreatic Tail Swelling Associated with Incretin-based Therapies Detected Radiologically in Two Cases of Diabetic Patients with End-Stage Renal Disease
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概要
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We herein report two cases of pancreatitis associated with incretin-based therapies in end-stage renal disease (ESRD) patients undergoing dialysis. A 75-year-old woman with a history of liraglutide use and a 68-year-old man with a history of vildagliptin use both presented with nausea. They showed elevated levels of pancreatic enzymes and pancreatic tail swelling on CT. Their symptoms improved after discontinuing the drugs. In the absence of any obvious secondary causes of pancreatitis, we believe that the pancreatitis observed in these cases was associated with the incretin-based therapies. Few reports have been published on the safety and efficacy of incretin-based therapies in ESRD patients, and it remains uncertain whether the changes in the pancreas observed in the present cases are characteristic of ESRD patients.
著者
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Inoue Gen
Department Of Chemical Engineering Graduate School Of Engineering Kyushu University
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Sugitani Seita
Department of Nephrology, Japanese Red Cross Society Wakayama Medical Center, Japan
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Nakata Hirosuke
Department of Diabetes and Endocrinology, Wakayama Medical Center Japanese Red Cross Society, Japan
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Otsu Satoko
Department of Nephrology, Japanese Red Cross Society Wakayama Medical Center, Japan
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Yamaji Shuhei
Department of Nephrology, Japanese Red Cross Society Wakayama Medical Center, Japan
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Higashi Yoshihito
Department of Nephrology, Japanese Red Cross Society Wakayama Medical Center, Japan
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Ohtomo Yumiko
Department of Nephrology, Japanese Red Cross Society Wakayama Medical Center, Japan
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