三次元頭部実体モデルによる脳深部ひずみ分布の計測と脳形状因子の影響

概要

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The purpose of this study is to clarify the strain distribution within deep brain and influence of brain shape factors on the strain distribution by using three dimensional physical head models during rotational impact. Three different shaped brain models were constructed; actual human brain shape model, no-ventricle model and simplified shape model. Angular acceleration pulse, whose peak of 4500 rad/s2 with 8 ms pulse duration, was induced to the models. After rotating 60 degree, all models were decelerated with 1500 rad/s2 peak with 30 ms duration. As for the strain distribution within deep brain inducing actual human brain, strain concentrations were measured at corpus callosum and brain stem. This was due to constraint of cerebrum brain rotational motion by falx and tentorium and hollow shape of ventricle. The maximum principal strain at brainstem in no-ventricle brain model was larger than the actual brain shape model. However the strain distributed near the corpus callosum in no-ventricle brain model was smaller than the actual brain shape model. The strain in the simplified brain shape model was smaller compared with other brain models. Therefore the cerebral ventricle relieved strain at brainstem and increased the strain near the corpus callosum. On the other hands, the sulci has a influences of increasing strain within deep brain.