A convenient method for preparation of 2-(methylthio)alkanoic acids and their related compounds using the carbanions of substituted malonic esters.
スポンサーリンク
概要
- 論文の詳細を見る
Starting from alkyl- or aryl-substituted malonic esters prepared by various methods, 2-(methylthio)alkanoic acids are synthesized by successive treatment with sodium ethoxide and with S-methyl methanethiosulfonate, followed by alkaline hydrolysis which causes concurrent decarboxylation. Production of 2-(phenylthio)alkanoic acids is also achieved in a similar manner.
- 公益社団法人 日本化学会の論文
著者
-
Morita Toshio
Department Of Applied Chemistry And Biotechnology Faculty Of Engineering Fukui University
-
Ogura Katsuyuki
Department Of Applied Chemistry And Biotechnology Faculty Of Engineering Chiba University
-
Itoh Hiroshi
Department Of Advanced Materials Science Faculty Of Engineering Kagawa University
-
Morita Toshio
Department of Synthetic Chemistry, Faculty of Engineering, Chiba University
-
Iida Hirotada
Department of Synthetic Chemistry, Faculty of Engineering, Chiba University
-
Sanada Kunio
Department of Synthetic Chemistry, Faculty of Engineering, Chiba University
-
Iida Hirotada
Department of Industrial Chemistry and Synthetic Chemistry, Faculty of Engineering, Chiba University
関連論文
- New Approaches to Blockade of the Renin–Angiotensin–Aldosterone System: Characteristics and Usefulness of the Direct Renin Inhibitor Aliskiren
- Possible roles of human (pro)renin receptor suggested by recent clinical and experimental findings
- Antifungal Cyclodepsipeptides, W493 A and B, from Fusarium sp. : Isolation and Structural Determination
- Immunogenetical Study in Patients with Chronic Glomerulonephritis
- Experimental atrial fibrillation originated from the pulmonary vein : Importance of vagal stimulation and driving force
- Synergistic Augmentation of Neovascularizaiton by Transplantation of Human ES Cells-derived Endothelial Cells and Mural Cells-Approach Towards Hybrid Stem Cell Therapy(The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Effects of DHMEQ, a Novel Nuclear Factor-κB Inhibitor, on Beta Cell Dysfunction in INS-1 Cells
- Combination of C-reactive Protein and High Molecular Weight (HMW)-Adiponectin Reflects Further Metabolic Abnormalities Compared with Each of Them Alone in Japanese Type 2 Diabetic Subjects
- 4 Application of Natriuretic Peptides to Peripheral Artery Occlusive Diseases (PAOD)(New Progress in Clinical Application of Natriuretic Peptide Family,Roundtable Discussion 1 (RT1) (H),The 70th Anniversary Annual Scientific Meeting of the Japanese Circul
- Identification of Vascular Progenitor Cells from Human Embryonic Stem Cells and their Application to Vascular Regeneration Therapy(The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Adrenomedullin Promotes Proliferation and Migration of Cultured Endothelial Cells
- Direct phosphorylation and inactivation of small GTPase RhoA by cGMP-dependent protein kinase and its implication in vascular remodeling
- Contribution of embryonic stem (ES) cell-derived vascular progenitor cells (VPC) to blood vessel formation during adult neoangiogenesis
- New Diagnostic Procedure for Primary Aldosteronism: Adrenal Venous Sampling under Adrenocorticotropic Hormone and Angiotensin II Receptor Blocker-Application to a Case of Bilateral Multiple Adrenal Microadenomas
- IS161 Rho-associated Kinase as a Critical Regulator of Proliferation and Migration of Vascular Smooth Muscle Cells Both in vitro and in vivo
- Monosynaptic Excitatory Connection from the Rostral Ventrolateral Medulla to Sympathetic Preganglionic Neurons Revealed by Simultaneous Recordings
- Apoptosis of hypertrophic chondrocytes in rat cartilaginous growth plate
- Drug Discovery for Overcoming Chronic Kidney Disease (CKD) : New Therapy for CKD by a (Pro)Renin-Receptor-Blocking Decoy Peptide
- (Pro)Renin Receptor-Mediated Activation of Mitogen-Activated Protein Kinases in Human Vascular Smooth Muscle Cells
- cDNA Sequencing and Expression of Rat Mast Cell Tryptase^1
- Prevention and regression of hypertension : role of renal microvascular protection
- Developmental Activity of the Renin-Angiotensin System during the "Critical Period" Modulates Later L-NAME-Induced Hypertension and Renal Injury
- Targered re-differentiation of proliferating vascular smooth muscle cells through cGMPcascade activation using adenoviral vector for C-type natriuretic peptide
- An autopsy case of Duchenne muscular dystrophy with severe mental retardation, showing multifocal glial nodules in the cerebral cortex.
- Eosinophil Peroxidase Deficiency in Humans and Mice
- Expression of Prostaglandin E Receptor EP_4 Subtype in Rat Adrenal Zona Glomerulosa: Involvement in Aldosterone Release
- Melatonin alleviates jet lag symptoms caused by an 11-hour eastward flight
- Effect of 3mg melatonin on jet lag syndrome in an 8-h eastward flight
- Sleep architectures of obstructive sleep apnea syndrome in the young child
- Changes in subjective sleepiness, subjective fatigue and nocturnal sleep after anaesthesia with propofol
- Morita Therapy and Sleep Hygiene
- Re-entrainment of circadian rhythm of plasma melatonin on an 8-h eastward flight
- Clinical features of circadian rhythm sleep disorders in outpatients
- Downregulation of Urokinase-Type and Tissue-Type Plasminogen Activators in a Rabbit Model of Renal Ischemia/Reperfusion
- Electro- and Thermomigration of Metallic Islands on Si(100) Surface
- Differentiation from embryonic stem cells to vascular wall cells under in vitro pulsatile flow loading
- 4-(4-Pyridyl)benzoic Acid (PybenH) Dimer : An Efficient and Reasonable Design for a Long Linear Bidentate Building Block Employed in Metal-Organic Coordination Framework
- Effects of Telmisartan Therapy on Metabolic Profiles and Serum High Molecular Weight (HMW)-Adiponectin Level in Japanese Male Hypertensive Subjects with Abdominal Obesity
- Structural and Catalytic Properties of Silica-Coated Alumina
- Trabecular Pattern Analysis Using Fractal Dimension
- Comparative Study on Caustic and Enzymatic Cleanings of Stainless Steel Surface Fouled with β-Lactoglobulin
- Adsorption of β-Lactoglobulin onto the Surface of Stainless Steel Particles
- Successful treatment of primary aldosteronism due to computed tomography-negative microadenoma
- Establishment and Characteristics of Four Sub-Strains of F344 Rats Reared on Various Low Protein and Low Energy Diets
- Expression of Inter-α-Trypsin Inhibitor Light Chain (Bikunin) in Human Pancreas
- Relationship between Maximal Pulmonary Ventilation and Arterialized Venous Blood Potassium and Dopamine Concentrations Obtained at Exhaustion in Man
- ADAM-mediated ectodomain shedding of HGF activator inhibitor type 1 (HAI-1) regulates pericellular activation of hepatocyte growth factor (HGF)
- The Short Treatment with the Angiotensin Receptor Blocker Candesartan Surveyed by Telemedicine (STAR CAST) Study : Rationale and Study Design
- Ultrafast Quantum Beats and Optical Dephasing of Exciton Systems in β-ZnP_2 by Spectrally Resolved Four-Wave Mixing
- Coordination Polymers Self-Assembling from Cadmium(II) Ions and Flexible Pyridine-Based Bridging Ligands
- Application of ES Cells to Cardiovascular Regeneration
- Papillary Thyroid Carcinoma without Metastases Manifesting as an Autonomously Functioning Thyroid Nodule
- Translational medicine of natriuretic peptide family
- Preparation of Microporous Silica Gel by Sol-Gel Process in the Presence of Ethylene Oligomers
- 2 A Novel role of Adrenomedullin/cyclic AMP Pathway in Arterial Endothelial Cell Differentiation(Angiogenesis-Clinical and Experimental New Findings,Symposium 3 (SY3) (H),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Novel Solvent-Free Reactions with Iodine : Solid-Solid and Solid-Vapor Reactions of 1-Aryl-4-(methylthio)-2-(p-tolylsulfonyl)-1, 3-butadienes
- Crystal Structure of a Complex between p-Nitrophenol and 2-Pyridone
- Facile Formation of Stable Crystals with Gold-like Metallic Luster from Organic Molecules: 1-Aryl-2-(2-thienyl)-5-[5-(tricyanoethenyl)-2-thienyl]pyrroles
- Novel Emitting Materials for Organic Electroluminescent Device:1-Aryl-2, 5-di(2-thienyl)pyrrole Derivatives Having an Electron-withdrawing Group
- Impaired Guanosine 3', 5'-Cyclic Phosphate Production in Severe Pregnancy-Induced Hypertension with High Plasma Levels of Atrial and Brain Natriuretic Peptides
- Effect of an SF_6 Additive on a TE CO Laser
- Improved Performance of a Pulsed CO Laser with Xylene Additive
- Novel Synthesis of α-Amino Carboxamides and Their Related Compounds via α-Oxo Sulfones Starting from 2, 2-Disulfonyloxiranes
- Studies on the Meerwein Arylation-Based Preparation of 2,3-Diarylbenzene-1,4-diones and Its Theoretical Interpretation
- Temperature Dependent Duplex Formation of 3'-Phosphate Bearing α-2'-Deoxyoctathymidylate Phosphorothioate and Polyriboadenylic Acid Complex
- Acute interstitial nephritis associated with ulcerative colitis
- A Novel Reaction Promoted by Hydrogen Polyiodides (HI_) : Cyclization of 1-(1H-3-Indolyl)-4-(methylthio)-2-(p-tolylsulfonyl)-1,3-butadienes Accompanied with 1,2-Sulfonyl Migration
- Facile Optical Resolution of a Dibenzopyrazinoazepine Derivative and the Nature of Molecular Recognition of Amines by Chiral 2, 3-Di-O-(arylcarbonyl)tartaric Acids
- New Approaches to Blockade of the Renin-Angiotensin-Aldosterone System : Characteristics and Usefulness of the Direct Renin Inhibitor Aliskiren
- Exciton dephasing in (AlAs)_m/(GaAs)_n various period superlattices
- Stimulated Emission from the A^1?^+_u of Sodium Dimer
- A Chiral Tweezers-Type Dicarboxylic Acid: Studies on Its Complexation With Amines Utilizing CD Spectrum
- Convenient Synthesis of Angular Triquinane from 4-Alkenylfulvene via Thermal Cycloaddition Followed by Skeletal Rearrangement of the Resulting [4 + 2] Adduct
- Subpicosecond Photon Echo Quantum Beats in a Dye-Doped Polymer
- The cell-cell interaction between Astroglia and Microglia in HIV-1 Infected Brains
- ESTIMATION OF LYSINE IN FEEDS BY THE USE OF L(+)-LYSINE DECARBOXYLASE
- Novel Synthesis of γ-Lactones Starting from β, γ-Unsaturated Carboxylic Esters
- Abnormal Four-Membered Ring Formation in Intramolecular Radicalic Cyclization. High Stability of the Alkyl Radical Substituted with Methylthio and p-Tolylsulfonyl Groups
- Effects of Three Types of Control Devices on Closed-Type Supersonic Cavity Flows
- Experimental Investigation on the Mechanism of Flow-Type Changes in Supersonic Cavity Flows
- Supramolecular Self-Assembly of Macrocycles, Catenanes, and Cages through Coordination of Pyridine-Based Ligands to Transition Metals
- CALCIUM METABOLISM IN THE RABBIT II. TIME DISTRIBUTION OF INTRAVENOUSLY ADMINISTERED RADIOCALCIUM IN THE YOUNG RABBIT
- CALCIUM METABOLISM IN THE RABBIT III. TIME DISTRIBUTION OF INTRAVENOUSLY ADMINISTERED RADIOCALCIUM IN THE MATURE RABBIT
- A STUDY OF THE CALCIUM IN LEGUME FORAGES
- A New Type of Memory Light Valve with a Mixture of Smectic and Cholesteric Liquid Crystals
- A Novel Synthesis of Highly Branched-Alkyl Aryl Ketones Using the Conjugate Addition of the Gilman Lithio Cuprate to β-Methylthio-α,β-unsaturated Ketones : Abnormal Reactivity of the Intermediary Enolates toward Molecular Oxygen
- Lipase-Catalyzed Practical Synthesis of (R)-1-Benzyl-3-hydroxy-2, 5-pyrrolidinedione and Its Related Compounds
- High 1, 2-Asymmetric Induction in Radical Reactions : Radical Addition to γ-Hydroxy α, β-Unsaturated Carboxylic Esters and Sulfones
- Specific Inclusion of 1,2-Dimethoxybenzene Derivatives by Crystalline (R)-Arylglycyl-(R)-phenylglycines and Its Structure
- Optional Formation of "Parallel or Antiparallel"β-Sheet-like Structures in (R)-(1-Naphthyl)glycyl-(R)-phenylglycine Crystals
- Smectic Liquid Crystal Imaging Devices Based on a Photochemical Reaction
- Oxidation of methyl (methylthio)methyl sulfoxide.
- The triflic acid-catalysed deacylation and decarboxylation of polymethylbenzenecarbonyl derivatives under mild conditions.
- 2-(Trifluoroacetyloxy)pyridine as a mild trifluoroacetylating reagent of amines and alcohols.
- A convenient method for preparation of 2-(methylthio)alkanoic acids and their related compounds using the carbanions of substituted malonic esters.
- Convenient preparation of methylthiomethyl p-tolyl sulfone starting from dimethyl sulfoxide.
- Catalytic activity of PdCl2 complexes having sulfur compounds as ligands.
- Photoinduced Reactions. XLIII. Photochemical Reactions of 4-Hydroxy-2,5-cyclohexadienones
- Stereocontrolled reduction of 2-(p-tolylsulfinyl)cycloalkanones under basic conditions: .PI.-Facial selection in cyclic systems directed by a chiral side chain.
- Efficient preparation of 3-alkyl(or aryl)thio-1(or 2)-propenyl p-tolyl sulfones.