Sulfur-extrusive rearrangement of .ALPHA.-acylthio ester by lithium amide.

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概要

• 論文の詳細を見る

• α-Acylthio esters readily undergo facile rearrangement to give β-keto esters on treatment with lithium amide at −78°C. Thiolactone <B>3</B>, a key intermediate for thiolactonic antibiotics, was synthesized by utilizing the rearrangement.

• 公益社団法人 日本化学会の論文

著者

• Omura Satoshi

  School Of Pharmaceutical Sciences Kitasato University And Kitasato Institute

• TSUZUKI Kazuo

  School of Human Care Studies, Nagoya University of Arts and Sciences

• Akeyoshi Masaharu

  School of Pharmaceutical Sciences, Kitasato University and The Kitasato Institute

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