Studies on the Secondary Structure of Bradykinin in Aqueous Solution. Syntheses, Circular Dichroism Spectra, and Biological Activities of Bradykinin Amide and (D-Ala4)-Bradykinin.
スポンサーリンク
概要
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Bradykinin amide and [D-Ala<SUP>4</SUP>]-bradykinin were synthesized by the 'hold-in-solution' method. The circular dichroism spectra of both peptides were measured and compared with that of bradykinin. These analogs exhibited weak activity (0.01% of bradykinin) in the increment of blood flow in a femoral artery of dog.
- 公益社団法人 日本化学会の論文
著者
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Muramatsu Ichiro
Department Of Chemistry College Of Science Rikkyo University
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Hashimoto Chikao
Department Of Chemistry Jikei University School Of Medicine
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Nozaki Sukekatsu
Faculty Of Pharmaceutical Sciences Josai University
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