第三脳室を占拠した混合性胚細胞性腫瘍の診断と治療

概要

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We are using a protocol to have made the chemotherapy by cyclophosphamide (CPA), etoposide (VP16), Cisplatin (CDDP), and vincristine(VCR) to the cases of mixed germ cell tumor. At this protocol, When a remaining neoplasm is recognized at the end of the 4th course of chemotherapy, it will do high dose chemotherapy which taken thiotepa (TESPA) and melphalan (L-PAM) together with peripheral blood stem cell transplantation (PBSCT) for the 5th course. This time, We experienced 2 patients of mixed germ cell tumor, the neoplasm disappeared only by chemo-radiotherapyl in 1 Patient and was able to get good result in doing salvage surgery to the remaining neoplasm in the other patient. When the neoplasm remains after the chemo-radiotherapy, salvage surgery is recommended. In addition, it should consider that it makes adjuvant therapy without histological diagnosis to the case that the tumor marker is raising.
近畿脳腫瘍病理検討会の論文