The Efficacy of Prophylactic Adminstration for the Treatment of Japanease Cedar or Japanese Cypress Pollinosis

概要

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The clinical effect as well as the effect on quality of life (QOL) of ebastine were evaluated in Japanese ceder pollen allergy patients by comparing treatment before the start of pollen season and treatment after pollen had been scattered.Seventy-seven cases could be evaluated for efficacy and safety and sixty-nine were assessed for QOL.1) Based on the symptom score method, treatment before the pollen season showed a lower score than treatment at later time.2) Based on the medication score method, there were no significant differences.3) Assessment of QOL using JRQLQ showed a lower score indicating a higher QOL in patients cases treated before the start of the pollen season.These findings suggest that prophylactic ebastine is useful for the treatment of Japanese ceder pollinosis, even when there was a small quantity of pollen.