内耳疾患とメコリ-ル点眼試験 (メニエ-ル病の研究-3-<特集>)

概要

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The positive rates of abnormal miosis following the application of 5% mecholyl solution to the eyes increased on the affected side in the following order of during intervals, adjunctive spells, and definitive spells in cases of Meniere's disease. The test results were compared with those obtained from patients with sudden deafness, labyrinthitis, and vestibular neuronitis. 1) Five out of 17 cases (29%) of sudden deafness showed positive reactions on the affected side, when examined within two weeks after the onset of the disease. In the five cases showing positive reactions, three had no vertigo or objective findings.2) Five patients with labyrinthitis and four patients with vestibular neuronitis were examined by the mecholyl test. In no patient was the abnormal miosis limited to the affected side.These results demonstrate that the mecholyl test is not positive merely as the result of an abnormality of the vestibulo-autonomic reflex. Therefore, the positive mecholyl tests in cases of Meniere's disease indicate a dysfunction of the autonomic nervous system on the affected side.
耳鼻咽喉科臨床学会の論文