頭蓋内より波及した内耳炎 (滋賀医科大学耳鼻咽喉科学教室開講3周年記念論文集<特集>)

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Temporal bones acquired from early stage of meningitis offer clinical and histopathological interest on their initial route of invasion and the site of tissues involved first in the labyrinth.We acquired a pair of temporal bones from a patient who died of very early stage of meningitis.Histopathological study revealed that the infection extended from the cerebrospinal fluid to the labyrinth not only through the cochlear aqueduct but also along the cochlear and vestibular nerve fibers. Early degenerative changes consisted of swelling and detachment of hair cells from Deiters', disintegration of the strial cells were paralleled the extent of leucocytes invasion, resulting greater changes in the basal turn.Localized otitis media was revealed at the round window niche, where the inflammatory cells passed through the round window membrane.
耳鼻咽喉科臨床学会の論文