Changes in arterial blood pressure during sleep in association with obstructive apnea.

概要

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Palygraphic recordings during spontaneous nocturnal sleep were made in four men, three of whom (age range, 35 to 62) had obstructive sleep apnea and one (age, 25) who had no apneic episodes. Continuous recordings were made simultaneously of finger arterial blood pressure, air flow, thoracic movement and mesopharyngeal pressure amplitude. One man with severe obstruction underwent tracheotomy and uvulopalatopharyngoplasty. He was studied again after surgery.1. When ventilation resumed, the blood pressure of the three patients with obstructive apnea rose. During apneic episodes, the blood pressure of two patients with severe obstruction gradually fell, while the blood pressures of one patient with mild obstruction was not reduced.2. One patient with severe obstruction showed irregular waves of blood pressure.3. One patient with severe obstruction, who was studied twice, had remarked fluctuations in blood pressure preoperatively and reducted and stable blood pressure postoperatively.4. The man with no apneic episodes showed transient elevations in blood pressure without periodicity.These results demonstrate that blood pressure is affected by repetitive obstructive apnea and that measurement of continuous finger arterial pressure is clinically useful and totally harmless.
耳鼻咽喉科臨床学会の論文