.BETA.-endorphin levels in cerebrospinal fluid of patients with various spinal disorders: Correlation with pain.:Correlation with Pain

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We measured by radioimmunoassay β-endorphin levels in cerebrospinal fluids of thirty-seven patients, who had various kinds of spinal disorders (mainly lumbar disk lesion).Group 1: thirty patients with pain who had lumbar disk hernia, spondylolytic spondylisthesis, tumor, trauma, etc.Group 2: seven patients without pain who had chronic quadriplegia by cervical spinal injury, spinal cord degeneration, etc.We concluded that β-endorphin level in cerebrospinal fluid is low in the patients with pain in Group 1.
西日本整形・災害外科学会の論文