RFP治療により菌陰性化を示した再治療肺結核症例よりの再陽転症例の検討

概要

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Authors published already the results of the follow up studies of retreatment pulmonary tuberculosis patients who showed negative sputum for more than 3 months at 6th month after starting the treatment with regimens containing rifampicin. Cumulative rate of positive reconversion was 19.3% during 7 years' observation period. Most of them showed positive sputum within one and half years after starting rifampicin treatment, and no relation was found whether the caces continuing rifampicin treatment or not.<BR>In this study, 73 cases, which showed positive reconversion, were compared with 73 matched-pair cases, which were taken at random from the negative sputum group, for the purpose of finding out the risk factors concerning the positive reconversion of sputum. As the results, higher risk of positive reconversion was observed in the following cases;<BR>1) cases converted to negative by RFP treatment relatively late.<BR>2) cases whose chest roentgenogram did not improve or worsened, and<BR>3) cases which had already acquired resistance to main antituberculous drugs.
一般社団法人日本結核病学会の論文