トリ型菌類似の病原性を示す非定型抗酸菌嶋本株に関する知見補遺

概要

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In order to identify the Shimamoto strain of an atypical acid-fast bacillus, which showed the similar pathogenicity for rabbits to that of Mycobacterium avium, histologic changes seen in the visceral organs of rabbits, pathogenicity for chickens and some biochemical characteristics of organism were compared with those of M. avium and Battey bacilli. In rabbits infected with the Shimamoto strain, epithelioid cell tubercles, which were morphologically indistinguishable from those produced by the Kirchberg strain of M. avium, were revealed in the lungs, liver and spleen. However, the lesions were a little less extensive in the Shimamoto group. In addition, the number of mycobacteria detected in tissue sections from viscera of the Shimamoto group was fewer than that of the Kirchberg group. On the other hand, in rabbits infected with the Gamoh strain of atypical Battey bacillus, no histologic changes were revealed in the lungs, and the granulomatous lesions in the liver and spleen were in a very limited degree only. No acid-fast bacilli were detected in tissue sections made from viscera.
一般社団法人日本結核病学会の論文