CHANGES IN THE COUNT OF TUBERCLE BACILLI PRESENT IN THE SPUTUM OF THE PATIENTS TREATED WITH ISONICOTINIC ACID HYDRAZID IN RELATION TO THE INCREASE IN THE APPEARANCE OF RESISTANT BACILLI

概要

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TREATMENT being done on 18 cases of pulmonary tuberculosis with INAH alone (0.2g per day orally) or INAH in combination with either SM (2g per week intramuscularly) or PAS (8-10g per day orally), the investigation was made on the relationship between the changes in the count of tubercle bacilli present ii their sputum and the increase in the appearance of resistant bacilli. The changes in the count of tubercle bacilli were observed by Ogawa's quantitative cultivation method. For the detection of the appearance of resistant bacilli, direct couplings were made on 3% KH<SUB>2</SUB>PO<SUB>4</SUB> (Ogawa's medium). Following are the findings obtained thereof
一般社団法人日本結核病学会の論文