悪性黒色腫8例の臨床的検討

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Primary malignant melanoma of the oral cavity is rare, and few reports of this type of tumor have dealt with a large number of cases. Eight patients with oral malignant melanoma treated in the Department of Oral Surgery, School of Medicine, Gunma University, during the past 12 years have been studied clinico-pathologically. The results are as follows: 1. Malignant melanoma constituted about 4.8% of all the cases of oral malignancy during the same period. 2. The age ranged from 30 to 67 years with a mean age of 52.6 years. Three cases occurred in the seventh decade, two in sixth, one in fifth and one in fourth. There were two males and six females. 3. As for the areas involved, six cases were afflicted in upper gum or hard palate, one in lower gum and one in submaxillary area. 4. As for clinical features, three cases were characterizedby just flat spot, and five by tumor-like masses. All of the cases were black in color with one exception, which occurred in the submaxillary area. Four cases were ulcerated and four nonulcerated. 5. Microscopically, six cases were of spindle cell type, one of round cell type and another of intermediate type. 6. All cases were treated by irradiation and five of them were additionally treated by surgery. All cases were treated with chemotherapy and immunotherapy or cryosurgery. The metastatic lymphonodes were treated by irradiation. 7. The prognosis of seven of the cases was grave and the prognosis of one was excellent. At present, the latter has survived two years and five months after the initial visit.

悪性黒色腫8例の臨床的検討

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