A case of malignant acanthosis nigricans.

概要

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A rare case of malignant acanthosis niglicans associated with lung cancer in a 70 year-01d male who showed various immunolegical disorders including antinuclear antibodies and CEA is presented.<BR>The main symptoms and signs werc a rough feeling of the lips and tongue, formation of many papillary tumors 1-2mm in diameter, papillary hyperplasia of the cheeks and the resulting formation of grooves, pigmentation of the Iips and the mucosa of the cheeks, furrodwed tongue and loss of taste sensation.<BR>The administration of cisplatin, doxorubicin and mitomycin C resulted in marked regression of the lung cancer, and the oral lesions showed marked improvement in association with the improvement in the immunological disorders. The improvement in the oral Iesions was also shown in the histopathological findirags.
社団法人日本口腔外科学会の論文