口腔領域悪性腫瘍の臨床病理学的検討 : 第7報舌癌Stage I, II症例の頸部リンパ節後発転移について

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Characteristics of cervical metastasis after treatment without local recurrence in Stage I and II of tongue cancer were investigated from clinico-pathological findings.<BR>Metastasis after treatment was found in 5 out of 23 cases.The incidence of lymphnode metastasis by therapeutic modality indicated that cervical metastasis occurred in one case (8.3%) treated by surgery, and in 4 cases (36.4%) of those treated with radiotherapy. In these 4 cases, the total dose of radiation to the primay lesion ranged from 8, 500 rads to 15, 959 rad, and averaged 11, 840 rad. Duration from the time of starting the treatment to that of palpation of cervical metastasis was 4-7 months.<BR>Location of metastasis nodes were level I and II in the level of involvement proposed by the UICC.Clinically, the metastatic rate was 33.3% in T1, 14.7% in T2, 22.2% in exophytic growth type, and 20.0% in endophytic growth type.Histologically, these cases were classified into three of grade 2 (4/8, 50.0%) and one of grade 4 D (1/1, 100%) in the mode of invasion.On the differentiation of the tumor, metastasis was found in 2 cases (18.2%) of well differentiated, in 2 cases (22.2%) of moderately differentiated and in one case (33.3%) of poorly differentiated.<BR>C. P. the 4 cases in which metastasis occurred were low grade malignancies.This suggested that metastasis that occured after treatment was related to the therapeutic method.