A case of acquired lymphadenopathic toxoplasmosis with submental lesion.

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Toxoplasmosis is an infectious disease common both in humen and animals. There are congenital and acquired manifestations of this condition. We had a case of a 10-year-old boy with a painless mass resembling a lymph node in the submental lesion of about four days duration. The indirect hemagglutination test which is one of the toxoplasma serologic tests was suspected positive. Excisional biopsy revealed a dark-red, well-capsulated tumor. Histopathologically, the excised lymph node showed reactive hyperplasia with small clusters of epithelioid histiocytes. These small clusters were composed of variable numbers of epithelioid histiocytes distributed throughout the paracortex and cortex. Tingible body macrophages were seen in the secondary reactive follicles. There was no necrosis nor caseation, and giant cells were rarely seen. Neither distinct toxoplasma, nor cystic form of it was identified in histological sections, but an immunohistochemical test showed positive reaction. Following the biopsy, toxoplasmosis titer was varying. But the patient recovered uneventfully and the follow-up has remained asymptomatic.
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