左側頬粘膜部に発生した腺房細胞腫の1例 : 光学顕微鏡的および電子顕微鏡的観察

概要

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A case of acinic cell tumor arising in the buccal mucosa of a 59-year-old man was reported. The tumor mass was 2.5×2.0×2.0cm and encapusulated.<BR>Histologically, the tumor was composed of serous cells. These cells contained many basophilic granules which were PAS-positive, diastase-resistant, mucicarmine negative and alcian blue negative. Ultrastrcturally, large rounded or polyhedral tumor cells contained numerous secretory granules which varied in size, shape and electron density. These cells were similar to the serous cells of the normal acini. A few smaller cells lacking secretory granules were also seen. These cells were round or cuboidal and simliar to the intercalated duct cells of normal salivary glands. Their cytoplasm was electron-lucent and contained a small amount of cytoplasmic organella. The nuclei were large and oval shape.<BR>In the present case, this tumor was composed of two types of cells, which were the predominant secretory cells and the intercalated ductlike cells.