多数歯埋伏を伴った大理石骨病の1例

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Osteopetrosis is a rare disorder characterized by symmetrical systemic sclerosis of skeletal bone which gives rise to susceptibility to fracture and osteomyelitis. Frequently dentition development is affected. A case of osteopetrosis in a 20-year-old female including various forms of dentition disorders i.e., impaction of 765 678 E3 B3, distorted crowns of 5 5, enamel hypoplasia of 43 3 4 4, arrested root development of 35, curved roots of 3 3, delayed root development of 5 and dentigerous cyst of 3, is described. In family history, the parents were consanguinity and the younger brother died of unknown etiology at one year old. Systemic roentogenological examination revealed characteristic findings e.g., sclerosis of the base of skull, "sandwich" appearance of the spine, "bone within a bone" appearance of the epiphises of long bones. By clinical examinations, anemia and cerebral nerve palsy were not observed. The serum calcium, phosphorus, alkaline phosphatase, thyrocalcitonin and parathormone levels were within normal limits. Impacted E3 B and 3 associated with dentigerous cyst were surgically removed under local anesthesia and intravenous dripping infusion of piperacillin. The wounds healed uneventfully. Microscopically, hyperplastic cementum of the root of 3 showed ankylosis with bone. Sclerosed cancellous bone of the mandible was composed of thickened lamellar bone exhibiting mosaic pattern with cement lines.
社団法人日本口腔外科学会の論文

多数歯埋伏を伴った大理石骨病の1例

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