下顎骨に発生したセメント質形成性線維腫の1例

概要

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The cementifying fibroma is a rare benign fibro-osseouse lesion of the jaw, and is generally believed to originate from the periodontal ligament, which possesses the capacity to form cementum, and alveolar bone and fibrous tissues. We present a case of central cementifying fibroma with an impacted tooth in the mandible. The patient was a 28-year-old woman who, since age 15, had noticed diffuse swelling in the region of the right mandible. Multiple angle radiography and CT scanning demonstrated well-defined radiolucent area on the right side of the body of the mandible, exhibiting sharply circumscribed borders and containing irregular radiopaque areas and an impacted tooth. The tumor was completely excised by a segmental mandiblectomy as lower cortical bone was found to be resorped. Immediate reconstruction was undertaken using an aluminaceramic mandibular prosthesis. Microscopic examination of the tumor revealed a spindle cell stroma containing collagen fibers surrounding various-sized islands of hard cementum-like tissue. Based on these findings a diagnosis of cementifying fibroma was reached.