Time-related changes in the fixation strength of titanium bone screw after implantation.

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In the field of oral surgery, titanium bone screws are used for plate fixation in the treatment of jaw fractures and maxillary degeneration, but there have been very few reports on the time course of changes during relatively short fixation. To investigate fixation changes in titanium bone screws with the passage of time, we implanted titanium bone screws with a defined screwing torque in the femoral bone of the rat, and then progressively measured the loosening torque and bone destructing torque in the period from immediately after until 8 weeks after implantation. In addition, new bone formation and calcification around the screw and in its periphery were observed macroscopically and by soft radiography; histological examination was then performed at the time exhibiting the greatest dynamic change.<BR>The following results were obtained from this investigation. Fixation strength of titanium bone screws decreased with time, reaching a minimum 2 weeks after implantation. By 8 weeks after implantation, fixation strength was higher than that immediately after implantation. These findings indicated that the fixation strength of titanium bone screws used for anchorage in oral surgery decreases progressively until 2 weeks after implantation. This suggests the need for some form of adjuvant fixation until 3 weeks after implantation; in addition, strong occlusal force and mandibular movement that might loosen the fixed site should be avoided.
社団法人日本口腔外科学会の論文

Time-related changes in the fixation strength of titanium bone screw after implantation.

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