Spirocyclic Acylphloroglucinol Derivatives from Hypericum beanii
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概要
- 論文の詳細を見る
Four new acylphloroglucinols with an unusual 6/6/5 spirocyclic skeleton, hyperbeanols A—D (1—4), were isolated from the methanol extract of Hypericum beanii along with 16 known compounds. Their structures were established on the basis of spectroscopic and X-ray diffraction analysis. Hyperbeanols A—C were three stereoisomers different only at the relative configuration of C-4 and C-13, which were distinguished by the nuclear Overhauser effect spectroscopy (NOESY) spectroscopic data in combination with the single X-ray analysis of hyperbeanol A (1). The cytotoxic activity of hyperbeanols A—D against the cancer cell lines SK-BR-3, HL-60, SMMC-7721, PANC-1, MCF-7, and K562 was also evaluated.
著者
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Li Yan
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Peng Li-yan
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Xu Gang
State Key Laboratory Of Phytochemistry And Plant Resources In West China Kunming Institute Of Botany
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Li Yan
Institute Of Medicinal Plant Development Chinese Academy Of Medical Sciences And Peking Union Medica
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Chen Xuan-Qin
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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He Juan
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Pan Zheng-Hong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Cheng Xiao
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botan
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Zhao Qin-shi
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Li Ming-ming
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Wang Kou
State Key Lab. Of Phytochemistry And Plant Resources In West China Kunming Inst. Of Botany Chinese A
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Li Kun-Zhi
Biotechnology Research Center, Kunming University of Science and Technology
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Pan Zheng-Hong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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Xu Gang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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He Juan
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences
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