出産時偶然に悪性黒色腫が発見されたdysplastic nevusの1例

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We report a case of sporadic dysplastic novus associated with malignant melanoma. A 29-year-old Japanese female had been noticed a black nodule on her right buttock three years duration and was first recommended to consult it to our clinic by agynecologist after her first delivery. The nodule was flatly elevated and 18×8mm in diameter. Histological examination of the nodule revealed superficial spreading melanoma, Clarks level IV with a maximal tumor thickness of 1.8mm. There were metastases in the inguinal and parailiac lymph nodes. Aphysical examination revealed a total of ca. 120 brownish macules ranging from 2 to 9mm in diameter on her whole body surface. She had paler skin and sunburned easily. Four of these pigmented macules were histologically diagnosed as dysplastic nevi. Family history revealed neither dysplastic nevi nor malignant melanoma. This is a fifteenth report of a Japanese patient developing malignant melanoma in association with dysplastic nevi.