A case of malignant fibrous histiocytoma.

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The case was a 76 year-old female. She had a simple excision of a subcutaneous nodule done to her left buttock by a local doctor and came to our hospital when regional relapse occurred. At the time of the operation, which was one month after she had been admitted to our hospital, left inguinal lymphnode swellings were recognized. Histopathologically, the tumor consisted of fibroblast like cells with nucleus of various sizes and histiocyte like cells with cylinder shaped bright cytoplasm. A few giant cells were also found scatterly. Cells arranged in strif orm pattern were also found and we diagnosed it as a case of malignant fibrous histiocytoma. After radical excision with left groin lymphnode resection, 2 courses of chemotherapy of ADR 40mg and CDDP 50mg were commenced but relapsed occurred again. By radiation treatment, the tumor reduced in size transiently. Metastasis to the lungs and bones occured and the patient died one and a half years after the initial diagnosis.
日本皮膚悪性腫瘍学会の論文