A Case of Posttraumatic Hypopituitarism
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概要
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A case of posttraumatic hypopituitarism was studied. A 46-years-old man suffered from adrenal crisis after he showed symptoms of hypopituitarism which was caused by the head injury of 26 years ago. Hyponatremia was prominent at the time of admission. Clinical and laboratory studies revealed hypothyroidism, hypofunction of adrenal gland and hypogonadism. Blood pituitary hormones-ACTH, GH, TSH and LH were determined by radioimmunoassay. Plasma ACTH levels were not detectable (below 10pg/m<I>l</I>) even after metyrapone administration. Base-line serum GH level was low and did not respond to the administration of insulin or L-arginine. Although the response was subnormal, serum TSH levels were increased in response to synthetic thyrotropin releasing hormone (TRH). Serum LH levels were low. Mechanism about the hyponatremia at the time of adrenal crisis in this case was discussed.
- 社団法人 日本内分泌学会の論文
著者
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Irie Minoru
First Department Of Medicine Toho University School Of Medicine
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Kanayama Yoshiharu
Osaka City University Medical School
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Kubo Kenji
Department Of Neurological Surgery Wakayama Medical University
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Wada Masahisa
Department Of Applied Biological Chemistry The University Of Tokyo
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Nakai Yoshikatsu
Second Division, Department of Medicine, Kyoto University School of Medicine
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Furukawa Yoko
Department Of Preventive Cardiology National Cerebral And Cardiovascular Center
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KANAYAMA YOSHIHARU
Department of Internal Medicine, Osaka City University Medical School
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MORII HIROTOSHI
Department of Internal Medicine, Osaka City University Medical School
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Nakai Yoshikatsu
Second Division Department Of Medicine Kyoto University School Of Medicine
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Kubo Kenji
Department Of Electrical Engineering Faculty Of Engineering Science Osaka University:(present Addres
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Furukawa Yoko
Department Of Health And Nutrition Faculty Of Health Science Kyoto Koka Women's University
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FURUKAWA YOKO
Department of Internal Medicine, Osaka City University Medical School
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IRIE MINORU
First Department of Internal Medicine, Faculty of Medicine, Toho University
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WADA MASAHISA
Department of Internal Medicine, Osaka City University Medical School
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