Increased Renal Kallikrein Excretion in SIADH after Vincristine Therapy
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概要
- 論文の詳細を見る
This is a report about a 14-year old girl who, following chemotherapy for malignant teratoma, developed a clinical state of SIADH (syndrome of inappropriate secretion of antidiuretic hormone).<BR>The causative agent was most likely vincristine (VCR). The important feature in this case was that the urinary kallikrein activity was high when she was affected by SIADH and decreased when her hyponatremia improved. Sodium clearance was significantly correlated with the increase in urinary kallikrein activity. It is considered that the kallikrein-kinin system may in part participate in the excessive natriuresis of SIADH.
- 社団法人 日本内分泌学会の論文
著者
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Suzuki Hidenori
Department Of Cardiovascular Research Tokyo Metropolitan Institute Of Medical Science
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TOMITA MASAKO
Department of Paediatrics Tokyo Medical and Dental University
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MATSUOKA YOSHIKO
Department of Paediatrics Tokyo Medical and Dental University
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SAKURADA NORIYUKI
Department of Paediatrics Tokyo Medical and Dental University
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Suzuki Hidenori
Department of Applied Physics, Tokyo University of Science, 1-3 Kagurazaka, Shinjuku-ku, Tokyo 162-8601
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