Glycosylation of 3, 5, 3-L-Triiodothyronine and its Biological Activity
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概要
- 論文の詳細を見る
The formation of glycosylated Hb by the nonenzymatic reaction between Hb and glucose suggests that glycosylation is a general reaction in the living body. We demonstrated by means of TLC and HPLC that T<SUB>3</SUB> was glycosylated when reacted with glucose in absolute ethanol for a week. We demonstrated in a metamorphic study in tadpoles that the biological activity of thus glycosylated T<SUB>3</SUB> was less than about 1/10 of that of T<SUB>3</SUB>.<BR>These findings suggest that glycosylation of substances with amino group other than serum proteins including Hb may occur and that glycosylated substances may differ in biological activities from the original substances.
- 社団法人 日本内分泌学会の論文
著者
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Baba Shigeaki
The Second Department Of Internal Medicine Kobe University School Of Medicine
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Oimomi Munetada
Faculty Of Health Science And Second Department Of Medicine Kobe University School Of Medicine
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OIMOMI Munetada
The Second Department of Internal Medicine, Kobe University School of Medicine
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YOSHIMURA YUKIO
The Second Department of Internal Medicine, Kobe University School of Medicine
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ISHIKAWA KAZUO
The Second Department of Internal Medicine, Kobe University School of Medicine
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KAWASAKI TOMIHIRO
The Second Department of Internal Medicine, Kobe University School of Medicine
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KUBOTA SHINZO
The Second Department of Internal Medicine, Kobe University School of Medicine
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