ビタミンKの抗菌作用機構-4-

概要

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Previously the effect of vitamin K compounds on various enzymatic activities of Escherichiacoli was studied, and the interfering effects of the compounds on the activities of enzymes involving SH groups were observed. In this paper the effect of the compounds on some microbial hydrolytic enzymes has been studied. And using certain enzymes, the active group or groups of which had been ascertained, some investigations were undertaken to demonstrate that the compounds never inhibit any other active groups of enzymes than SH. (1) The activities of mold protease, yeast invertase, pancreas amylase and trypsin (activegroups of these enzymes are amino, tyrosyl or certain groups and not SH) were not affected by the compounds even at a higher degree of concentrations than that which permits the microbes to grow. (2) β-amylase, the active group of which is SH, was inhibited by the compounds. (3) The only possible interfering point of the compounds with enzymes is active SH group.
社団法人日本水産学会の論文