防腐劑の作用機構に関する研究(第1報) : HexamethylenetetramineとFormaldehydeの殺菌並に静菌作用に就て

概要

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Earlier works on the antibacterial action of preservatives were chiefly concerned with studying the variation in toxicity from one member of a homologous series to the next and there was scarcely anything on the mode of the action. Accordingly, the writer intend to report in this paper some observations which throw light on the mechanism of antibacterial action of hexamethylenetetramine and formaldehyde. The results obtained are as follows; (1). The bactericidal and bacteriostatic actions of hexamethylenetetramine are attributed to the free formaldehyde in its solution (Table 1, 2 and Fig. 3). (2). The bacteriostatic efficiency of formaldehyde is not markedly increased by increases of hydrogen-ion concentration (Fig. 4). (3). The inhibitory effect of formaldehyde on the growth of Escherichia coli is repressed by cysteine (Fig. 7).
公益社団法人日本水産学会の論文