Comparison of organic acids in three parts of the human heart by gas chromatography-mass spectrometry.

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概要

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• Organic acids from left ventricle (LV), papillary muscle (PM) and right auricle (RA) of hearts from patients with valvular heart diseases, were analyzed using gas chromatography-mass spectrometry (GC/MS) and compared. Peaks of 2-deoxytetronate and dideoxypentonate were generally small, smallest in PM and largest in LV. Peaks of 3-deoxy-2-C-(hydroxymethyl) tetronate, 3-deoxyerythropentonate and 3-deoxy-2-C-(hydroxymethyl) erythropentonate were, however, comparatively large. They were largest in RA and the smallest in PM. This work shows that deoxyaldonic acids are, generally, contained in small amounts in the human heart.

• 久留米大学医学部 The Kurume Medical Journal 編集部の論文

著者

• Ohishi Kiroku

  Department Of 2nd Surgery Kurume University School Of Medicine

• Koga Michihiro

  Department Of 2nd Surgery Kurume University School Of Medicine

• Takagi Hiromi

  Department Of Fine Materials Engineering Faculty Of Textile Science And Technology Shinshu Universit

• Toshima Hironori

  Department Of Cardiology Kurume University Medical Center

• KUHARA TOMIKO

  Research Institute of Medical Mass Spectrometry, Kurume University School of Medicine

• MATSUMOTO ISAMU

  Research Institute of Medical Mass Spectrometry, Kurume University School of Medicine

• HARAGUCHI SHIN-ICHI

  Department of Internal Medicine, Kurume University School of Medicine

• SHINKA TOSHIHIRO

  Research Institute of Medical Mass Spectrometry, Kurume University School of Medicine

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